HitPredict

Interactor 1: AP2A (P91926)
AP-2 complex subunit alpha (Alpha-adaptin)
Gene: AP-2alpha

Interactor 2: Q7KT38 (Q7KT38)
non-specific serine/threonine protein kinase (EC 2.7.11.1)
Gene: Nak

Species: Drosophila melanogaster

Source: biogrid

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.68	0.60	0.640

Property	Details
Experiments	22017988, 19258011, 22036573
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0008356 - asymmetric cell division
Homologous interactions	15

Homologous interactions

Color coding for hit scores

	1 940 Dm			1 698
+	Hs
		302160 AP2A2_HUMAN (1-940): 0: 829: 69.18		AAK1_HUMAN (1-442): 8.42e-142: 440: 51.58
+	Hs
		321559 AP2A1_HUMAN (1-940): 0: 815: 65.48		AAK1_HUMAN (1-442): 8.42e-142: 440: 51.58
+	Hs
		302214 AP2A2_HUMAN (1-940): 0: 829: 69.18		BMP2K_HUMAN (37-429): 5.59e-127: 406: 54.32
+	Hs
		321653 AP2A1_HUMAN (1-940): 0: 815: 65.48		BMP2K_HUMAN (37-429): 5.59e-127: 406: 54.32
+	Dm
		1096899 Q24253_DROME (33-933): 0: 624: 15.26		Q7KT38_DROME (1-698): 1.91e-163: 488: 100.00
+	Hs
		925884 AP2B1_HUMAN (33-935): 0: 669: 16.31		AAK1_HUMAN (1-442): 8.42e-142: 440: 51.58
+	Hs
		1014021 AP1B1_HUMAN (33-935): 0: 654: 15.41		AAK1_HUMAN (1-442): 8.42e-142: 440: 51.58
+	Dm
		1181922 Q7KVR8_DROME (4-705): 0: 592: 25.31		Q7KT38_DROME (1-698): 1.91e-163: 488: 100.00
+	Hs
		926022 AP2B1_HUMAN (33-935): 0: 669: 16.31		BMP2K_HUMAN (37-429): 5.59e-127: 406: 54.32
+	Hs
		1014089 AP1B1_HUMAN (33-935): 0: 654: 15.41		BMP2K_HUMAN (37-429): 5.59e-127: 406: 54.32
+	Hs
		926058 AP2B1_HUMAN (33-935): 0: 669: 16.31		AKT3_HUMAN (1-383): 1.21e-122: 375: 17.84
+	Hs
		161600 AP2A2_HUMAN (1-940): 0: 829: 69.18		GAK_HUMAN (20-322): 2.48e-44: 173: 38.14
+	Hs
		161603 AP2A1_HUMAN (1-940): 0: 815: 65.48		GAK_HUMAN (20-322): 2.48e-44: 173: 38.14
+	Hs
		212600 AP1G1_HUMAN (6-820): 0: 590: 22.60		AKT2_HUMAN (6-385): 1.67e-120: 370: 17.95
+	Hs
		161644 AP2B1_HUMAN (33-935): 0: 669: 16.31		GAK_HUMAN (20-322): 2.48e-44: 173: 38.14