HitPredict

Interactor 1: RAB10 (P61026)
Ras-related protein Rab-10 (EC 3.6.5.2)
Gene: RAB10

Interactor 2: MICA1 (Q8TDZ2)
[F-actin]-monooxygenase MICAL1 (EC 1.14.13.225) (EC 1.6.3.1) (Molecule interacting with CasL protein 1) (MICAL-1) (NEDD9-interacting protein with calponin homology and LIM domains)
Gene: MICAL1

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	1.00	0.621

Property	Details
Experiments	21900206
Identification Methods	two hybrid
Interaction Type	direct interaction

Property	Details
Interacting Pfam domains	Ras~bMERB_dom
Common GO terms	GO:0005829 - cytosol GO:0005886 - plasma membrane GO:0005929 - cilium GO:0010008 - endosome membrane
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 200 Hs			1 1067
+	Hs
		955977 RAB8A_HUMAN (1-199): 1.02e-96: 281: 67.32		MICA1_HUMAN (1-1067): 0: 1251: 100.00
+	Hs
		981326 RAB1A_HUMAN (1-200): 5.86e-86: 254: 50.24		MICA1_HUMAN (1-1067): 0: 1251: 100.00
+	Hs
		1352051 RAB1B_HUMAN (3-200): 5.16e-85: 251: 50.50		MICA1_HUMAN (1-1067): 0: 1251: 100.00
+	Mm
		313238 RAB10_MOUSE (1-200): 7.58e-88: 258: 100.00		ACTN3_MOUSE (430-1064): 8.4e-128: 413: 12.40
+	Hs
		976210 RB11A_HUMAN (3-200): 5.58e-82: 244: 40.19		SPTB2_HUMAN (430-1064): 4.2e-110: 380: 14.93
+	Ce
		111187 G5EFC1_CAEEL (1-197): 2.07e-97: 283: 67.82		G5ECW3_CAEEL (428-1061): 1.65e-85: 298: 14.50
+	Ce
		111189 RAB10_CAEEL (1-200): 2.05e-84: 249: 70.15		G5ECW3_CAEEL (428-1061): 1.65e-85: 298: 14.50
+	Hs
		1313738 RAB8B_HUMAN (1-198): 2.03e-100: 290: 70.20		MILK2_HUMAN (748-1059): 8.85e-46: 180: 19.44
+	Hs
		1325129 RAB8B_HUMAN (1-198): 2.03e-100: 290: 70.20		MILK1_HUMAN (769-1051): 2.85e-43: 172: 21.68
+	Mm
		1189526 RAB13_MOUSE (1-200): 1.35e-90: 265: 62.00		MILK2_MOUSE (752-1059): 1.29e-50: 196: 19.32
+	Hs
		955961 RAB8A_HUMAN (1-199): 1.02e-96: 281: 67.32		MILK2_HUMAN (748-1059): 8.85e-46: 180: 19.44
+	Hs
		955971 RAB8A_HUMAN (1-199): 1.02e-96: 281: 67.32		EHBP1_HUMAN (636-1055): 4.43e-44: 176: 13.41
+	Hs
		955965 RAB8A_HUMAN (1-199): 1.02e-96: 281: 67.32		MILK1_HUMAN (769-1051): 2.85e-43: 172: 21.68
+	Hs
		956749 RAB10_HUMAN (1-200): 7.58e-88: 258: 100.00		MILK1_HUMAN (769-1051): 2.85e-43: 172: 21.68
+	Hs
		902207 RAB13_HUMAN (4-174): 1.52e-83: 247: 69.59		MILK2_HUMAN (748-1059): 8.85e-46: 180: 19.44
+	Hs
		1273853 RAB8B_HUMAN (1-198): 2.03e-100: 290: 70.20		MICA3_HUMAN (582-1053): 3.47e-30: 131: 19.03
+	Hs
		902209 RAB13_HUMAN (4-174): 1.52e-83: 247: 69.59		MILK1_HUMAN (769-1051): 2.85e-43: 172: 21.68
+	Hs
		955951 RAB8A_HUMAN (1-199): 1.02e-96: 281: 67.32		MICA3_HUMAN (582-1053): 3.47e-30: 131: 19.03
+	Hs
		956742 RAB10_HUMAN (1-200): 7.58e-88: 258: 100.00		MICA3_HUMAN (582-1053): 3.47e-30: 131: 19.03
+	Hs
		976366 RB11A_HUMAN (3-200): 5.58e-82: 244: 40.19		MICA3_HUMAN (582-1053): 3.47e-30: 131: 19.03