Interactor 1: SHPS1 (P97797)
Tyrosine-protein phosphatase non-receptor type substrate 1 (SHP substrate 1) (SHPS-1) (Brain Ig-like molecule with tyrosine-based activation motifs) (Bit) (CD172 antigen-like family member A) (Inhibitory receptor SHPS-1) (MyD-1 antigen) (Signal-regulatory protein alpha-1) (Sirp-alpha-1) (mSIRP-alpha1) (p84) (CD antigen CD172a)
Gene: Sirpa

Interactor 2: SHPS1 (P97797)
Tyrosine-protein phosphatase non-receptor type substrate 1 (SHP substrate 1) (SHPS-1) (Brain Ig-like molecule with tyrosine-based activation motifs) (Bit) (CD172 antigen-like family member A) (Inhibitory receptor SHPS-1) (MyD-1 antigen) (Signal-regulatory protein alpha-1) (Sirp-alpha-1) (mSIRP-alpha1) (p84) (CD antigen CD172a)
Gene: Sirpa

Species: Mus musculus

Source: biogrid

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.33 1.00 0.575

The method score is based on:

Property Details
Experiments 18045614
Identification Methods x-ray crystallography
Interaction Type association

The annotation score is based on:

Property Details
Interacting Pfam domains C1-set~C1-set, C1-set~V-set, V-set~V-set
Common GO terms GO:0001933 - negative regulation of protein phosphorylation
GO:0002244 - hematopoietic progenitor cell differentiation
GO:0005886 - plasma membrane
GO:0006910 - phagocytosis, recognition
GO:0006911 - phagocytosis, engulfment
and 35 others

more...

Homologous interactions 16

Homologous interactions

Color coding for hit scores

1 513
Mm

1 513
+ Mm
+ Hs
+ Hs
+ Hs
+ Hs
+ Hs
+ Hs
+ Hs
+ Hs
+ Hs
+ Hs
+ Hs
+ Hs
+ Hs
+ Dr
+ Dr

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Last updated: 15 Jul 2024