Protein: P4HA2
Prolyl 4-hydroxylase subunit alpha-2 (4-PH alpha-2) (EC 1.14.11.2) (Procollagen-proline,2-oxoglutarate-4-dioxygenase subunit alpha-2)

Gene: P4HA2
Organism: Homo sapiens
Interactions: 131
UniProt ID: O15460

Gene Ontology (top 5):
GO:0004656 - procollagen-proline 4-dioxygenase activity
GO:0005506 - iron ion binding
GO:0005654 - nucleoplasm
GO:0005783 - endoplasmic reticulum
GO:0005788 - endoplasmic reticulum lumen

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

179998

PDIA1
Protein disulfide-isomerase

5

11

High-throughput

0.712

High

179997

CO1A1
Collagen alpha-1(I) chain

3

5

Small-scale

0.675

High

180003

P4HA1
Prolyl 4-hydroxylase subunit alpha-1

1

1

High-throughput

0.665

High

180006

CO8A2
Collagen alpha-2(VIII) chain

3

8

High-throughput

0.656

High

179995

CPSF4
Cleavage and polyadenylation specificity factor subunit 4

2

1

High-throughput

0.628

High

180048

FIP1
Pre-mRNA 3'-end-processing factor FIP1

2

2

High-throughput

0.628

High

180058

KI18B
Kinesin-like protein KIF18B

2

1

High-throughput

0.628

High

180086

WDR33
pre-mRNA 3' end processing protein WDR33

2

3

High-throughput

0.628

High

180038

KIF7
Kinesin-like protein KIF7

3

2

High-throughput

0.613

High

180068

NEK7
Serine/threonine-protein kinase Nek7

2

0

High-throughput

0.602

High

180063

TENS4
Tensin-4

2

1

High-throughput

0.594

High

179990

PRKN
E3 ubiquitin-protein ligase parkin

2

3

High-throughput

0.584

High

180039

MA7D1
MAP7 domain-containing protein 1

2

1

High-throughput

0.574

High

180042

TIGD5
Tigger transposable element-derived protein 5

2

2

High-throughput

0.574

High

180073

TTC28
Tetratricopeptide repeat protein 28

2

3

High-throughput

0.574

High

180021

BCAR1
Breast cancer anti-estrogen resistance protein 1

2

1

High-throughput

0.571

High

179989

CREB3
Cyclic AMP-responsive element-binding protein 3

2

0

High-throughput

0.565

High

70630

MYO9A
Unconventional myosin-IXa

1

1

High-throughput

0.536

High

151654

IRS4
Insulin receptor substrate 4

1

1

High-throughput

0.536

High

179987

WDR62
WD repeat-containing protein 62

1

1

High-throughput

0.536

High

179992

DNJB5
DnaJ homolog subfamily B member 5

1

1

High-throughput

0.536

High

179996

BAG3
BAG family molecular chaperone regulator 3

1

1

High-throughput

0.536

High

180000

ARAF
Serine/threonine-protein kinase A-Raf

1

4

High-throughput

0.536

High

180007

CO8A1
Collagen alpha-1(VIII) chain

1

8

High-throughput

0.536

High

180009

COIA1
Collagen alpha-1(XVIII) chain [Cleaved into: Endostatin; Non-collagenous domain 1

1

6

High-throughput

0.536

High

180010

TCPZ
T-complex protein 1 subunit zeta

1

2

High-throughput

0.536

High

180016

TCPG
T-complex protein 1 subunit gamma

1

1

High-throughput

0.536

High

180018

TSC2
Tuberin

1

1

High-throughput

0.536

High

180025

TCPB
T-complex protein 1 subunit beta

1

2

High-throughput

0.536

High

180026

COEA1
Collagen alpha-1(XIV) chain

1

3

High-throughput

0.536

High

180030

FOXF2
Forkhead box protein F2

1

4

High-throughput

0.536

High

180037

CPSF6
Cleavage and polyadenylation specificity factor subunit 6

1

5

High-throughput

0.536

High

180044

IQEC1
IQ motif and SEC7 domain-containing protein 1

1

1

High-throughput

0.536

High

180050

CO039
Uncharacterized protein C15orf39

1

2

High-throughput

0.536

High

180059

HSC20
Iron-sulfur cluster co-chaperone protein HscB

1

1

High-throughput

0.536

High

180066

ZN397
Zinc finger protein 397

1

1

High-throughput

0.536

High

180070

PSPC1
Paraspeckle component 1

1

1

High-throughput

0.536

High

180071

SYMPK
Symplekin

1

1

High-throughput

0.536

High

180079

ATX2
Ataxin-2

1

1

High-throughput

0.536

High

180080

COCA1

1

3

High-throughput

0.536

High

180081

TCPH
T-complex protein 1 subunit eta

1

1

High-throughput

0.536

High

180089

SAV1
Protein salvador homolog 1

1

2

High-throughput

0.536

High

180092

DISC1
Disrupted in schizophrenia 1 protein

1

1

High-throughput

0.536

High

180100

CPSF2
Cleavage and polyadenylation specificity factor subunit 2

1

2

High-throughput

0.536

High

180105

CPSF3
Cleavage and polyadenylation specificity factor subunit 3

1

2

High-throughput

0.536

High

164709

SC16A
Protein transport protein Sec16A

1

0

High-throughput

0.513

High

179991

IF4E2
Eukaryotic translation initiation factor 4E type 2

1

0

High-throughput

0.513

High

179993

RECQ4
ATP-dependent DNA helicase Q4

1

0

High-throughput

0.513

High

180004

H2AX
Histone H2AX

1

0

High-throughput

0.513

High

180011

PK3CB
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit beta isoform

1

0

High-throughput

0.513

High

180015

DPOD2
DNA polymerase delta subunit 2

1

0

High-throughput

0.513

High

180017

SRP09
Signal recognition particle 9 kDa protein

1

0

High-throughput

0.513

High

180019

ERF
ETS domain-containing transcription factor ERF

1

0

High-throughput

0.513

High

180028

IFFO1
Non-homologous end joining factor IFFO1

1

0

High-throughput

0.513

High

180029

FP100
Fanconi anemia core complex-associated protein 100

1

0

High-throughput

0.513

High

180031

TRI32
E3 ubiquitin-protein ligase TRIM32

1

0

High-throughput

0.513

High

180036

TAF1C
TATA box-binding protein-associated factor RNA polymerase I subunit C

1

0

High-throughput

0.513

High

180045

PKN3
Serine/threonine-protein kinase N3

1

0

High-throughput

0.513

High

180046

TRI65
E3 ubiquitin-protein ligase TRIM65

1

0

High-throughput

0.513

High

180047

RICTR
Rapamycin-insensitive companion of mTOR

1

0

High-throughput

0.513

High

180051

FA83H
Protein FAM83H

1

0

High-throughput

0.513

High

180054

ATG9A
Autophagy-related protein 9A

1

0

High-throughput

0.513

High

180055

CTU1
Cytoplasmic tRNA 2-thiolation protein 1

1

0

High-throughput

0.513

High

180057

ATG4D
Cysteine protease ATG4D

1

0

High-throughput

0.513

High

180065

SMG8
Nonsense-mediated mRNA decay factor SMG8

1

0

High-throughput

0.513

High

180069

CTF18
Chromosome transmission fidelity protein 18 homolog

1

0

High-throughput

0.513

High

180082

DCC1
Sister chromatid cohesion protein DCC1

1

0

High-throughput

0.513

High

180083

UT14A
U3 small nucleolar RNA-associated protein 14 homolog A

1

0

High-throughput

0.513

High

180088

SRMS
Tyrosine-protein kinase Srms

1

0

High-throughput

0.513

High

180095

RPC2
DNA-directed RNA polymerase III subunit RPC2

1

0

High-throughput

0.513

High

180096

TRM1
tRNA

1

0

High-throughput

0.513

High

180098

GTSE1
G2 and S phase-expressed protein 1

1

0

High-throughput

0.513

High

180103

MCM8
DNA helicase MCM8

1

0

High-throughput

0.513

High

180104

TSR3
18S rRNA aminocarboxypropyltransferase

1

0

High-throughput

0.513

High

180107

CHIP
E3 ubiquitin-protein ligase CHIP

1

0

High-throughput

0.513

High

174455

OGT1
UDP-N-acetylglucosamine--peptide N-acetylglucosaminyltransferase 110 kDa subunit

1

3

High-throughput

0.501

High

180012

PPIC
Peptidyl-prolyl cis-trans isomerase C

1

0

High-throughput

0.493

High

180023

RS13
Small ribosomal subunit protein uS15

1

0

High-throughput

0.493

High

180077

LURA1
Leucine rich adaptor protein 1

1

0

High-throughput

0.493

High

180087

AICDA
Single-stranded DNA cytosine deaminase

1

0

High-throughput

0.493

High

180091

SAS10
Something about silencing protein 10

1

0

High-throughput

0.493

High

180109

MORC2
ATPase MORC2

1

0

High-throughput

0.493

High

180020

DYN2
Dynamin-2

1

0

High-throughput

0.493

High

180053

UBP54
Inactive ubiquitin carboxyl-terminal hydrolase 54

1

1

High-throughput

0.489

High

180061

RAVR1
Ribonucleoprotein PTB-binding 1

1

1

High-throughput

0.489

High

180078

MA7D2
MAP7 domain-containing protein 2

1

2

High-throughput

0.489

High

180014

PRC2A
Protein PRRC2A

1

0

Small-scale

0.486

High

179988

TGON2
Trans-Golgi network integral membrane protein 2

1

3

High-throughput

0.479

High

179994

KI20A
Kinesin-like protein KIF20A

1

4

High-throughput

0.479

High

180002

PDIA4
Protein disulfide-isomerase A4

1

10

High-throughput

0.479

High

180013

SOX2
Transcription factor SOX-2

1

1

High-throughput

0.479

High

180022

SC61B
Protein transport protein Sec61 subunit beta

1

1

High-throughput

0.479

High

180024

RNF4
E3 ubiquitin-protein ligase RNF4

1

1

High-throughput

0.479

High

180032

CUL3
Cullin-3

1

1

High-throughput

0.479

High

180060

FA20C
Extracellular serine/threonine protein kinase FAM20C

1

1

High-throughput

0.479

High

180072

LRC59
Leucine-rich repeat-containing protein 59

1

2

High-throughput

0.479

High

180074

SCYL1
N-terminal kinase-like protein

1

2

High-throughput

0.479

High

180075

CALR3
Calreticulin-3

1

3

High-throughput

0.479

High

180101

ZRAN1
Ubiquitin thioesterase ZRANB1

1

1

High-throughput

0.479

High

180106

ALK
ALK tyrosine kinase receptor

1

4

High-throughput

0.457

High

180001

CFTR
Cystic fibrosis transmembrane conductance regulator

1

1

High-throughput

0.445

High

180064

RYBP
RING1 and YY1-binding protein

1

1

High-throughput

0.445

High

180049

SYNE3
Nesprin-3

1

2

High-throughput

0.437

High

180052

TRI67
Tripartite motif-containing protein 67

1

2

High-throughput

0.437

High

180093

T106B
Transmembrane protein 106B

1

3

High-throughput

0.437

High

180108

T22D4
TSC22 domain family protein 4

1

1

High-throughput

0.437

High

180008

BMI1
Polycomb complex protein BMI-1

1

0

High-throughput

0.426

High

180033

DYR1A
Dual specificity tyrosine-phosphorylation-regulated kinase 1A

1

0

High-throughput

0.426

High

180041

Q4VAQ0
COL8A2 protein

1

4

High-throughput

0.407

High

180102

TSYL4
Testis-specific Y-encoded-like protein 4

2

0

High-throughput

0.328

High

180056

CLNK
Cytokine-dependent hematopoietic cell linker

2

0

High-throughput

0.300

High

180034

FHL3
Four and a half LIM domains protein 3

1

0

High-throughput

0.299

High

61108

KRBA1
Protein KRBA1

1

0

High-throughput

0.279

Low

63707

CC85C
Coiled-coil domain-containing protein 85C

1

0

High-throughput

0.279

Low

119745

ARVC
Splicing regulator ARVCF

1

0

High-throughput

0.279

Low

150344

ZN195
Zinc finger protein 195

1

0

High-throughput

0.279

Low

179999

ZN865
Zinc finger protein 865

1

0

High-throughput

0.279

Low

180035

MELK
Maternal embryonic leucine zipper kinase

1

0

High-throughput

0.279

Low

180040

ERFE
Erythroferrone

1

0

High-throughput

0.279

Low

180062

TRM44
Probable tRNA

1

0

High-throughput

0.279

Low

180067

SHKB1
SH3KBP1-binding protein 1

1

0

High-throughput

0.279

Low

180084

K1671
Uncharacterized protein KIAA1671

1

0

High-throughput

0.279

Low

180085

TNG6
Transport and Golgi organization protein 6 homolog

1

0

High-throughput

0.279

Low

180090

MYO5C
Unconventional myosin-Vc

1

0

High-throughput

0.279

Low

180027

DMWD
Dystrophia myotonica WD repeat-containing protein

1

0

High-throughput

0.269

Low

180043

VP13D
Intermembrane lipid transfer protein VPS13D

1

0

High-throughput

0.269

Low

180099

SACS
Sacsin

1

0

High-throughput

0.269

Low

180005

EFNA1
Ephrin-A1

1

0

High-throughput

0.249

Low

180094

KBTB4
Kelch repeat and BTB domain-containing protein 4

1

0

Small-scale

0.249

Low

180097

B3GN2
N-acetyllactosaminide beta-1,3-N-acetylglucosaminyltransferase 2

1

0

High-throughput

0.249

Low

180076

C170L
Cep170-like protein

1

0

High-throughput

0.232

Low


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Last updated: 15 Jul 2024