Interactor 1: IHH (P97812)
Indian hedgehog protein (IHH) (EC 3.1.-.-) (HHG-2) [Cleaved into: Indian hedgehog protein N-product]
Gene: IHH

Interactor 2: GPC3 (Q8CFZ4)
Glypican-3 [Cleaved into: Glypican-3 alpha subunit; Glypican-3 beta subunit]
Gene: GPC3

Species: Mus musculus

Source: biogrid

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.38 0.60 0.479

The method score is based on:

Property Details
Experiments 23665349
Identification Methods affinity chromatography technology
Interaction Type physical association

The annotation score is based on:

Property Details
Interacting Pfam domains -
Common GO terms GO:0005576 - extracellular region
GO:0005886 - plasma membrane
GO:0007224 - smoothened signaling pathway
GO:0040008 - regulation of growth
GO:0045880 - positive regulation of smoothened signaling pathway
Homologous interactions 2

Homologous interactions

Color coding for hit scores

1 411
Mm

1 579
+ Dm
+ Dm

Service provided by Combinatics, Japan

Last updated: 15 Jul 2024