HitPredict

Interactor 1: EYA1 (P97767)
Eyes absent homolog 1 (EC 3.1.3.16) (EC 3.1.3.48)
Gene: EYA1

Interactor 2: SIX1 (Q62231)
Homeobox protein SIX1 (Sine oculis homeobox homolog 1)
Gene: SIX1

Species: Mus musculus

Source: intact

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.80 1.00 0.898

The method score is based on:

Property Details
Experiments 11950062, 15492887, 15141091, 11734542
Identification Methods two hybrid, pull down, anti tag coimmunoprecipitation
Interaction Type direct interaction, physical association

The annotation score is based on:

Property Details
Interacting Pfam domains Hydrolase~SIX1_SD
Common GO terms GO:0001657 - ureteric bud development
GO:0001658 - branching involved in ureteric bud morphogenesis
GO:0003151 - outflow tract morphogenesis
GO:0005634 - nucleus
GO:0005654 - nucleoplasm
and 14 others

more...
Homologous interactions 20

Homologous interactions (Top 20)

Color coding for hit scores

1 591
Mm

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Service provided by Combinatics, Japan

Last updated: 15 Jul 2024