HitPredict

Interactor 1: DAB2 (P98078)
Disabled homolog 2 (Adaptor molecule disabled-2) (Differentially expressed in ovarian carcinoma 2) (DOC-2) (Mitogen-responsive phosphoprotein)
Gene: DAB2

Interactor 2: SH3K1 (Q8R550)
SH3 domain-containing kinase-binding protein 1 (Regulator of ubiquitous kinase) (Ruk) (SH3-containing, expressed in tumorigenic astrocytes)
Gene: Sh3kbp1

Species: Mus musculus

Source: intact

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.50	0.437

Property	Details
Experiments	14596919
Identification Methods	anti bait coimmunoprecipitation
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	-
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 766 Mm			1 709
+	Hs
		957207 DAB2_HUMAN (1-766): 8.87e-80: 273: 81.76		SH3K1_HUMAN (1-709): 1.41e-127: 395: 88.15
+	Hs
		1268487 ANS1A_HUMAN (1-248): 2.57e-37: 152: 19.44		SH3K1_HUMAN (1-709): 1.41e-127: 395: 88.15
+	Hs
		269176 DAB1_HUMAN (11-617): 1.62e-37: 150: 23.57		SH3K1_HUMAN (1-709): 1.41e-127: 395: 88.15
+	Hs
		1115812 Q49AR9_HUMAN (1-280): 5.2e-36: 145: 17.87		SH3K1_HUMAN (1-709): 1.41e-127: 395: 88.15
+	Hs
		1191815 ANS1B_HUMAN (2-236): 1.85e-43: 172: 17.99		CD2AP_HUMAN (1-708): 1.38e-92: 303: 31.06
+	Hs
		1268522 ANS1A_HUMAN (1-248): 2.57e-37: 152: 19.44		CD2AP_HUMAN (1-708): 1.38e-92: 303: 31.06
+	Mm
		957157 DAB2_MOUSE (1-766): 9.01e-96: 316: 100.00		ITSN1_MOUSE (1-131): 1.6e-16: 86.3: 24.43
+	Hs
		557659 DAB2_HUMAN (1-766): 8.87e-80: 273: 81.76		NCK1_HUMAN (103-384): 1.76e-25: 110: 16.10
+	Hs
		957186 DAB2_HUMAN (1-766): 8.87e-80: 273: 81.76		ITSN1_HUMAN (205-465): 2.83e-17: 88.6: 15.81
+	Hs
		209098 ANS1B_HUMAN (2-236): 1.85e-43: 172: 17.99		NCK2_HUMAN (103-446): 5.13e-28: 118: 13.64
+	Mm
		223010 DAB1_MOUSE (11-617): 3.62e-37: 149: 24.35		NCK2_MOUSE (103-445): 1.71e-28: 120: 13.39
+	Hs
		208964 DAB1_HUMAN (11-617): 1.62e-37: 150: 23.57		NCK2_HUMAN (103-446): 5.13e-28: 118: 13.64
+	Dm
		112569 NUMB_DROME (24-531): 1.64e-38: 153: 11.91		M9ND00_DROME (273-580): 6.44e-25: 113: 14.58
+	Mm
		956235 DAB1_MOUSE (11-617): 3.62e-37: 149: 24.35		NCK1_MOUSE (103-384): 7.94e-26: 112: 16.10
+	Hs
		269120 DAB1_HUMAN (11-617): 1.62e-37: 150: 23.57		NCK1_HUMAN (103-384): 1.76e-25: 110: 16.10
+	Mm
		1206702 ANS1B_MOUSE (2-231): 5.14e-41: 164: 17.95		ITSN1_MOUSE (1-131): 1.6e-16: 86.3: 24.43
+	Hs
		269148 DAB1_HUMAN (11-617): 1.62e-37: 150: 23.57		ITSN1_HUMAN (205-465): 2.83e-17: 88.6: 15.81
+	Mm
		1206687 ANS1B_MOUSE (2-231): 5.14e-41: 164: 17.95		ARHG7_MOUSE (310-394): 1.31e-12: 73.2: 25.88
+	Ce
		60780 A5JYR4_CAEEL (5-289): 9.7e-38: 149: 28.91		Q9U2T9_CAEEL (202-401): 3.88e-14: 78.6: 18.72
+	Rn
		924995 SHC1_RAT (19-349): 2.08e-37: 148: 10.19		GRB2_RAT (318-390): 7.64e-15: 76.1: 32.43