HitPredict

Interactor 1: UB2D3 (P61077)
Ubiquitin-conjugating enzyme E2 D3 (EC 2.3.2.23) ((E3-independent) E2 ubiquitin-conjugating enzyme D3) (EC 2.3.2.24) (E2 ubiquitin-conjugating enzyme D3) (Ubiquitin carrier protein D3) (Ubiquitin-conjugating enzyme E2(17)KB 3) (Ubiquitin-conjugating enzyme E2-17 kDa 3) (Ubiquitin-protein ligase D3)
Gene: UBE2D3

Interactor 2: MARH5 (Q9NX47)
E3 ubiquitin-protein ligase MARCHF5 (EC 2.3.2.27) (Membrane-associated RING finger protein 5) (Membrane-associated RING-CH protein V) (MARCH-V) (Mitochondrial ubiquitin ligase) (MITOL) (RING finger protein 153) (RING-type E3 ubiquitin transferase MARCHF5)
Gene: MARCHF5

Species: Homo sapiens

Source: biogrid

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.41	0.60	0.501

Property	Details
Experiments	19741096
Identification Methods	pull down
Interaction Type	direct interaction

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0000209 - protein polyubiquitination GO:0051865 - protein autoubiquitination GO:0061630 - ubiquitin protein ligase activity GO:0070936 - protein K48-linked ubiquitination
Homologous interactions	6

Homologous interactions

Color coding for hit scores

	1 147 Hs			1 278
+	Hs
		906798 UB2D1_HUMAN (1-147): 3.03e-83: 242: 88.44		MARH5_HUMAN (1-278): 1.38e-162: 454: 100.00
+	Hs
		982340 UB2D2_HUMAN (1-147): 4.03e-83: 242: 97.28		MARH5_HUMAN (1-278): 1.38e-162: 454: 100.00
+	Hs
		1381209 UB2E3_HUMAN (4-146): 1.4e-74: 222: 65.73		MARH5_HUMAN (1-278): 1.38e-162: 454: 100.00
+	Hs
		909398 UB2E1_HUMAN (4-146): 3.07e-73: 218: 65.04		MARH5_HUMAN (1-278): 1.38e-162: 454: 100.00
+	Hs
		957852 UBE2N_HUMAN (4-147): 5.95e-69: 206: 46.53		MARH5_HUMAN (1-278): 1.38e-162: 454: 100.00
+	Dm
		762723 UBE2N_DROME (4-147): 3.74e-44: 143: 48.61		Q9VB61_DROME (10-278): 9.73e-143: 404: 39.71