HitPredict

Interactor 1: UBC12 (P61081)
NEDD8-conjugating enzyme Ubc12 (EC 2.3.2.34) (NEDD8 carrier protein) (Ubiquitin-conjugating enzyme E2 M)
Gene: UBE2M

Interactor 2: CSN2 (P61201)
COP9 signalosome complex subunit 2 (SGN2) (Signalosome subunit 2) (Alien homolog) (JAB1-containing signalosome subunit 2) (Thyroid receptor-interacting protein 15) (TR-interacting protein 15) (TRIP-15)
Gene: COPS2

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.74	0.60	0.667

Property	Details
Experiments	28514442, 28581483, 33961781
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005634 - nucleus GO:0005654 - nucleoplasm GO:0005829 - cytosol GO:0045116 - protein neddylation
Homologous interactions	5

Homologous interactions

Color coding for hit scores

	1 183 Hs			1 443
+	Hs
		127918 UBC12_HUMAN (1-183): 1.42e-69: 210: 100.00		PSD11_HUMAN (35-442): 5.46e-89: 278: 22.43
+	Hs
		957383 UBC12_HUMAN (1-183): 1.42e-69: 210: 100.00		PSMD6_HUMAN (55-440): 4.31e-87: 272: 13.01
+	Hs
		128194 UBC12_HUMAN (1-183): 1.42e-69: 210: 100.00		PSD12_HUMAN (39-440): 8.73e-83: 263: 12.80
+	Hs
		957346 UBC12_HUMAN (1-183): 1.42e-69: 210: 100.00		CSN1_HUMAN (17-443): 7.06e-80: 257: 15.02
+	Hs
		957497 UBC12_HUMAN (1-183): 1.42e-69: 210: 100.00		CSN4_HUMAN (54-440): 8.18e-74: 238: 16.25