Interactor 1: KCC2A (Q00168)
Calcium/calmodulin-dependent protein kinase type II alpha chain (CaM-kinase II alpha chain) (EC 2.7.11.17)
Gene: CaMKII

Interactor 2: CSKP (Q24210)
Peripheral plasma membrane protein CASK (dCASK) (EC 2.7.11.17) (Calcium/calmodulin-dependent protein kinase) (CAKI) (Camguk)
Gene: CASK

Species: Drosophila melanogaster

Source: intact

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.57 1.00 0.761

The method score is based on:

Property Details
Experiments 14687552
Identification Methods affinity chromatography technology, anti tag coimmunoprecipitation, anti bait coimmunoprecipitation, pull down
Interaction Type physical association, direct interaction

The annotation score is based on:

Property Details
Interacting Pfam domains CaMKII_AD~Pkinase, Pkinase~Pkinase
Common GO terms GO:0004674 - protein serine/threonine kinase activity
GO:0004683 - calmodulin-dependent protein kinase activity
GO:0005516 - calmodulin binding
GO:0005524 - ATP binding
GO:0007616 - long-term memory
and 3 others

more...

Homologous interactions 15

Homologous interactions

Color coding for hit scores

1 530
Dm

1 898
+ Mm
+ Mm
+ Hs
+ Rn
+ Mm
+ Rn
+ Mm
+ Dm
+ Mm
+ Rn
+ Hs
+ Hs
+ Hs
+ Hs
+ Hs

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Last updated: 15 Jul 2024