HitPredict

Interactor 1: NAM8 (Q00539)
Protein NAM8 (Nuclear accommodation of mitochondria protein 8) (U1 snRNP component NAM8)
Gene: NAM8

Interactor 2: NOP3 (Q01560)
Serine/arginine (SR)-type shuttling mRNA binding protein NPL3 (Mitochondrial targeting suppressor 1 protein) (Nuclear polyadenylated RNA-binding protein 1) (Nuclear protein localization protein 3) (Polyadenylate-binding protein NPL3)
Gene: NPL3

Species: Saccharomyces cerevisiae S288C

Source: intact

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.79	1.00	0.892

Property	Details
Experiments	11805826, 19061647, 16429126, 21558325
Identification Methods	tandem affinity purification, affinity chromatography technology
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	RRM_1~RRM_1
Common GO terms	GO:0000398 - mRNA splicing, via spliceosome GO:0003729 - mRNA binding GO:0005634 - nucleus GO:0005737 - cytoplasm
Homologous interactions	19

Homologous interactions

Color coding for hit scores

	1 523 Sc			1 414
+	Sc
		376899 PABP_YEAST (3-323): 4.49e-41: 157: 12.87		NOP3_YEAST (1-414): 6.5e-65: 215: 100.00
+	Sc
		633980 NAM8_YEAST (1-523): 7.39e-89: 284: 100.00		GBP2_YEAST (124-272): 1.18e-16: 83.1: 25.86
+	Sc
		376895 NAM8_YEAST (1-523): 7.39e-89: 284: 100.00		PABP_YEAST (202-285): 1.62e-11: 68: 18.39
+	Hs
		516493 PABP1_HUMAN (153-523): 6.99e-36: 143: 13.78		SRSF9_HUMAN (118-264): 2.33e-47: 163: 27.81
+	Hs
		516478 PABP1_HUMAN (153-523): 6.99e-36: 143: 13.78		SRSF1_HUMAN (117-264): 1.06e-42: 152: 26.40
+	Zm
		8143 A0A1D6ELH4_MAIZE (3-457): 7.87e-36: 143: 11.93		A0A1D6ELH4_MAIZE (94-285): 1.13e-28: 120: 16.43
+	Hs
		1031344 PABP4_HUMAN (2-328): 3.82e-46: 172: 11.11		ELAV1_HUMAN (52-199): 2.71e-14: 75.2: 22.93
+	Hs
		1020249 PABP4_HUMAN (2-328): 3.82e-46: 172: 11.11		ELAV2_HUMAN (106-182): 7.18e-13: 71.4: 17.65
+	Hs
		1031490 PABP4_HUMAN (2-328): 3.82e-46: 172: 11.11		PUF60_HUMAN (199-352): 1.64e-12: 71.1: 13.75
+	Hs
		474021 PABP4_HUMAN (2-328): 3.82e-46: 172: 11.11		PAB4L_HUMAN (196-282): 1.21e-12: 70.7: 15.56
+	Hs
		516495 PABP4_HUMAN (2-328): 3.82e-46: 172: 11.11		PABP1_HUMAN (190-285): 3.21e-12: 70.3: 15.15
+	Sc
		376649 PABP_YEAST (3-323): 4.49e-41: 157: 12.87		GBP2_YEAST (124-272): 1.18e-16: 83.1: 25.86
+	Sc
		376562 PABP_YEAST (3-323): 4.49e-41: 157: 12.87		PABP_YEAST (202-285): 1.62e-11: 68: 18.39
+	Hs
		516484 PABP1_HUMAN (153-523): 6.99e-36: 143: 13.78		ELAV2_HUMAN (106-182): 7.18e-13: 71.4: 17.65
+	Hs
		516730 PABP1_HUMAN (153-523): 6.99e-36: 143: 13.78		PUF60_HUMAN (199-352): 1.64e-12: 71.1: 13.75
+	Hs
		516339 PABP1_HUMAN (153-523): 6.99e-36: 143: 13.78		PABP1_HUMAN (190-285): 3.21e-12: 70.3: 15.15
+	Hs
		516689 PABP1_HUMAN (153-523): 6.99e-36: 143: 13.78		PABP3_HUMAN (190-285): 3.3e-10: 63.7: 13.13
+	Hs
		516471 PABP1_HUMAN (153-523): 6.99e-36: 143: 13.78		TIAR_HUMAN (192-287): 2.59e-09: 60.7: 13.40
+	Hs
		516674 PABP1_HUMAN (153-523): 6.99e-36: 143: 13.78		RBM4_HUMAN (199-278): 2.55e-09: 60.7: 16.25