HitPredict

Interactor 1: DHSO (Q00796)
Sorbitol dehydrogenase (SDH) (EC 1.1.1.-) ((R,R)-butanediol dehydrogenase) (EC 1.1.1.4) (L-iditol 2-dehydrogenase) (EC 1.1.1.14) (Polyol dehydrogenase) (Ribitol dehydrogenase) (RDH) (EC 1.1.1.56) (Xylitol dehydrogenase) (XDH) (EC 1.1.1.9)
Gene: SORD

Interactor 2: DHSO (Q00796)
Sorbitol dehydrogenase (SDH) (EC 1.1.1.-) ((R,R)-butanediol dehydrogenase) (EC 1.1.1.4) (L-iditol 2-dehydrogenase) (EC 1.1.1.14) (Polyol dehydrogenase) (Ribitol dehydrogenase) (RDH) (EC 1.1.1.56) (Xylitol dehydrogenase) (XDH) (EC 1.1.1.9)
Gene: SORD

Species: Homo sapiens

Source: mint

Category: High-throughput

Confidence: High

Method score Annotation score Interaction score
0.89 1.00 0.943

The method score is based on:

Property Details
Experiments 25416956, 16189514, 21516116, 32296183, 31515488, unassigned1304
Identification Methods two hybrid, two hybrid array, two hybrid prey pooling approach, validated two hybrid, two hybrid pooling approach
Interaction Type direct interaction, physical association

The annotation score is based on:

Property Details
Interacting Pfam domains ADH_N~ADH_N, ADH_N~ADH_zinc_N, ADH_zinc_N~ADH_zinc_N
Common GO terms GO:0000721 - (R,R)-butanediol dehydrogenase activity
GO:0003939 - L-iditol 2-dehydrogenase (NAD+) activity
GO:0005615 - extracellular space
GO:0005829 - cytosol
GO:0006006 - glucose metabolic process
and 16 others

more...
Homologous interactions 15

Homologous interactions

Color coding for hit scores

1 357
Hs

1 357
+ Hs
+ Ce
+ Hs
+ At
+ Hs
+ Hs
+ Ce
+ Dm
+ Hs
+ Sc
+ Ph
+ Sc
+ At
+ Sc
+ Sc

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Last updated: 15 Jul 2024