Interactor 1: S61A1 (P61619)
Protein transport protein Sec61 subunit alpha isoform 1 (Sec61 alpha-1)
Gene: SEC61A1
Interactor 2: SEC63 (Q9UGP8)
Translocation protein SEC63 homolog (DnaJ homolog subfamily C member 23)
Gene: SEC63
Species: Homo sapiens
Source: biogrid
Category: High-throughput
Confidence: High
| Method score | Annotation score | Interaction score |
|---|---|---|
| 0.44 | 1.00 | 0.665 |
The method score is based on:
| Property | Details |
|---|---|
| Experiments | 33957083 |
| Identification Methods | affinity chromatography technology, proximity labelling technology |
| Interaction Type | physical association |
The annotation score is based on:
| Property | Details |
|---|---|
| Interacting Pfam domains | Sec63~SecY |
| Common GO terms | GO:0006614 - SRP-dependent cotranslational protein targeting to membrane GO:0006620 - post-translational protein targeting to endoplasmic reticulum membrane GO:0008320 - protein transmembrane transporter activity GO:0016020 - membrane GO:0031204 - post-translational protein targeting to membrane, translocation |
| Homologous interactions | 6 |
Service provided by Combinatics, Japan
Last updated: 11Aug2025