HitPredict

Interactor 1: SPTB2 (Q01082)
Spectrin beta chain, non-erythrocytic 1 (Beta-II spectrin) (Fodrin beta chain) (Spectrin, non-erythroid beta chain 1)
Gene: SPTBN1

Interactor 2: CEP63 (Q96MT8)
Centrosomal protein of 63 kDa (Cep63)
Gene: CEP63

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.68	0.60	0.641

Property	Details
Experiments	17043677, unassigned1973, 35709258
Identification Methods	two hybrid, two hybrid fragment pooling approach, anti bait coimmunoprecipitation
Interaction Type	direct interaction, physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005829 - cytosol
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 2364 Hs			1 703
+	Hs
		724781 SPTB2_HUMAN (1-2364): 0: 751: 100.00		MYH9_HUMAN (1-520): 3.09e-20: 98.3: 12.02
+	Hs
		148690 SPTB2_HUMAN (1-2364): 0: 751: 100.00		CTRO_HUMAN (22-572): 2.81e-16: 85.5: 13.29
+	Hs
		963381 SPTB2_HUMAN (1-2364): 0: 751: 100.00		MY18A_HUMAN (51-572): 5.91e-15: 81.2: 16.15
+	Hs
		211644 ACTN4_HUMAN (53-525): 6.51e-121: 409: 47.58		CEP63_HUMAN (1-703): 1.84e-64: 228: 100.00
+	Hs
		149277 SPTN4_HUMAN (5-2092): 2.42e-155: 540: 52.21		CTRO_HUMAN (22-572): 2.81e-16: 85.5: 13.29
+	Hs
		211515 ACTN4_HUMAN (53-525): 6.51e-121: 409: 47.58		MYH9_HUMAN (1-520): 3.09e-20: 98.3: 12.02
+	Hs
		148171 ACTN4_HUMAN (53-525): 6.51e-121: 409: 47.58		CTRO_HUMAN (22-572): 2.81e-16: 85.5: 13.29
+	Hs
		211632 ACTN4_HUMAN (53-525): 6.51e-121: 409: 47.58		MY18A_HUMAN (51-572): 5.91e-15: 81.2: 16.15
+	Hs
		1298045 CP250_HUMAN (220-2019): 1.07e-55: 218: 10.02		CEP63_HUMAN (1-703): 1.84e-64: 228: 100.00
+	Hs
		148722 ACTN3_HUMAN (41-776): 4.93e-97: 338: 33.73		CTRO_HUMAN (22-572): 2.81e-16: 85.5: 13.29
+	Hs
		521484 ACTN1_HUMAN (28-775): 4.31e-92: 323: 34.25		MYH9_HUMAN (1-520): 3.09e-20: 98.3: 12.02
+	Dm
		404218 ACTN_DROME (48-775): 2.3e-98: 342: 32.43		MYSA_DROME (1-419): 8.7e-13: 74.2: 14.45
+	Hs
		148339 ACTN1_HUMAN (28-775): 4.31e-92: 323: 34.25		CTRO_HUMAN (22-572): 2.81e-16: 85.5: 13.29
+	Hs
		360660 SPTA1_HUMAN (179-1394): 3.14e-92: 337: 19.60		CP250_HUMAN (150-696): 7.75e-10: 64.8: 11.94
+	Hs
		724994 CP250_HUMAN (220-2019): 1.07e-55: 218: 10.02		MYH9_HUMAN (1-520): 3.09e-20: 98.3: 12.02
+	Hs
		1113839 CP250_HUMAN (220-2019): 1.07e-55: 218: 10.02		GRDN_HUMAN (150-697): 6.94e-17: 87.5: 12.91
+	Mm
		93541 SPTA1_MOUSE (288-860): 3.62e-34: 147: 17.57		DESP_MOUSE (59-550): 4.18e-09: 62.5: 18.91
+	Hs
		724786 DYST_HUMAN (537-1421): 8.42e-22: 106: 12.00		MYH9_HUMAN (1-520): 3.09e-20: 98.3: 12.02
+	Hs
		148330 SPTB1_HUMAN (1359-2356): 5.1e-25: 117: 13.42		CTRO_HUMAN (22-572): 2.81e-16: 85.5: 13.29
+	Hs
		974117 DYST_HUMAN (537-1421): 8.42e-22: 106: 12.00		MY18A_HUMAN (51-572): 5.91e-15: 81.2: 16.15