Protein: DUS8
Dual specificity protein phosphatase 8 (EC 3.1.3.16) (EC 3.1.3.48) (Dual specificity protein phosphatase hVH-5)

Gene: DUS8, DUSP8
Organism: Homo sapiens
Interactions: 40
UniProt ID: Q13202

Gene Ontology (top 5):
GO:0004722 - protein serine/threonine phosphatase activity
GO:0005634 - nucleus
GO:0005737 - cytoplasm
GO:0007165 - signal transduction
GO:0008330 - protein tyrosine/threonine phosphatase activity

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

853672

MK08
Mitogen-activated protein kinase 8

6

20

High-throughput

0.950

High

853786

MK09
Mitogen-activated protein kinase 9

4

20

High-throughput

0.903

High

719137

MPIP1
M-phase inducer phosphatase 1

1

3

High-throughput

0.656

High

295497

PSD10
26S proteasome non-ATPase regulatory subunit 10

1

9

High-throughput

0.618

High

691727

MK03
Mitogen-activated protein kinase 3

1

20

High-throughput

0.618

High

703569

MK01
Mitogen-activated protein kinase 1

1

20

High-throughput

0.618

High

1098199

DUS8
Dual specificity protein phosphatase 8

1

15

High-throughput

0.618

High

1098202

DUS6
Dual specificity protein phosphatase 6

1

16

High-throughput

0.618

High

1098209

DUS16
Dual specificity protein phosphatase 16

1

16

High-throughput

0.618

High

1098204

ANKY2
Ankyrin repeat and MYND domain-containing protein 2

1

12

High-throughput

0.553

High

179504

ARPC3
Actin-related protein 2/3 complex subunit 3

1

1

High-throughput

0.479

High

916650

PPP5
Serine/threonine-protein phosphatase 5

1

9

High-throughput

0.479

High

963285

PFD3
Prefoldin subunit 3

1

3

High-throughput

0.479

High

987606

GRB2
Growth factor receptor-bound protein 2

1

9

High-throughput

0.479

High

995953

UB2L3
Ubiquitin-conjugating enzyme E2 L3

1

3

High-throughput

0.479

High

1014086

CBX1
Chromobox protein homolog 1

1

3

High-throughput

0.479

High

1097267

CBX3
Chromobox protein homolog 3

1

3

High-throughput

0.479

High

1098200

FKBP5
Peptidyl-prolyl cis-trans isomerase FKBP5

1

6

High-throughput

0.479

High

1098201

TEBP
Prostaglandin E synthase 3

1

3

High-throughput

0.479

High

1098203

FBX11
F-box only protein 11

1

3

High-throughput

0.479

High

1098205

OXR1
Oxidation resistance protein 1

1

1

High-throughput

0.479

High

1098208

NDUF3
NADH dehydrogenase [ubiquinone] 1 alpha subcomplex assembly factor 3

1

1

High-throughput

0.479

High

1098213

DBNL
Drebrin-like protein

1

6

High-throughput

0.479

High

293644

CD123
Translation initiation factor eIF2 assembly protein

1

0

High-throughput

0.458

High

1098210

WDR54
WD repeat-containing protein 54

1

0

High-throughput

0.458

High

1098216

SPIN1
Spindlin-1

1

0

High-throughput

0.458

High

289862

TIPRL
TIP41-like protein

1

1

High-throughput

0.437

High

866663

CAZA2
F-actin-capping protein subunit alpha-2

1

4

High-throughput

0.437

High

867090

CAPZB
F-actin-capping protein subunit beta

1

1

High-throughput

0.437

High

900795

RAB5C
Ras-related protein Rab-5C

1

8

High-throughput

0.437

High

963997

COPZ1
Coatomer subunit zeta-1

1

8

High-throughput

0.437

High

1098206

OTUB1
Ubiquitin thioesterase OTUB1

1

3

High-throughput

0.437

High

1098207

ERP44
Endoplasmic reticulum resident protein 44

1

1

High-throughput

0.437

High

1098211

NDUF4
NADH dehydrogenase [ubiquinone] 1 alpha subcomplex assembly factor 4

1

1

High-throughput

0.437

High

1098212

VPS29
Vacuolar protein sorting-associated protein 29

1

1

High-throughput

0.437

High

1098214

SGT1
Protein SGT1 homolog

1

2

High-throughput

0.437

High

1098215

PTH2
Peptidyl-tRNA hydrolase 2, mitochondrial

1

3

High-throughput

0.437

High

127489

NDUS8
NADH dehydrogenase [ubiquinone] iron-sulfur protein 8, mitochondrial

1

0

High-throughput

0.249

Low

281733

VP26A
Vacuolar protein sorting-associated protein 26A

1

0

High-throughput

0.249

Low


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Last updated: 11Aug2025