HitPredict

Interactor 1: SET (Q01105)
Protein SET (HLA-DR-associated protein II) (Inhibitor of granzyme A-activated DNase) (IGAAD) (PHAPII) (Phosphatase 2A inhibitor I2PP2A) (I-2PP2A) (Template-activating factor I) (TAF-I)
Gene: SET

Interactor 2: H2B1A (Q96A08)
Histone H2B type 1-A (Histone H2B, testis) (TSH2B.1) (hTSH2B) (Testis-specific histone H2B)
Gene: H2BC1

Species: Homo sapiens

Source: biogrid

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.41	1.00	0.647

Property	Details
Experiments	19358706
Identification Methods	pull down
Interaction Type	direct interaction

Property	Details
Interacting Pfam domains	Histone~NAP
Common GO terms	GO:0003677 - DNA binding GO:0005634 - nucleus GO:0005654 - nucleoplasm GO:0006334 - nucleosome assembly GO:0006337 - nucleosome disassembly and 1 others more... GO:0042393 - histone binding
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 290 Hs			1 127
+	Hs
		886086 SET_HUMAN (1-236): 6.45e-89: 268: 100.00		H2B1D_HUMAN (1-127): 1.37e-53: 166: 85.04
+	Hs
		707676 TSYL5_HUMAN (2-257): 3.11e-86: 265: 32.69		H2B1B_HUMAN (1-127): 6.87e-54: 166: 85.83
+	Hs
		707747 TSYL1_HUMAN (44-234): 2.32e-85: 264: 38.74		H2B1B_HUMAN (1-127): 6.87e-54: 166: 85.83
+	Hs
		876805 NP1L1_HUMAN (2-278): 1.56e-83: 258: 18.13		H2B2E_HUMAN (1-127): 4.39e-54: 167: 85.83
+	Hs
		707565 NP1L1_HUMAN (2-278): 1.56e-83: 258: 18.13		H2B1B_HUMAN (1-127): 6.87e-54: 166: 85.83
+	Hs
		876745 NP1L1_HUMAN (2-278): 1.56e-83: 258: 18.13		H2B1C_HUMAN (1-127): 8.19e-54: 166: 85.04
+	Hs
		876869 NP1L1_HUMAN (2-278): 1.56e-83: 258: 18.13		H2B1A_HUMAN (1-127): 1.72e-52: 163: 100.00
+	Hs
		1087365 NP1L4_HUMAN (4-242): 5.86e-81: 250: 18.81		H2B2E_HUMAN (1-127): 4.39e-54: 167: 85.83
+	Hs
		420873 NP1L4_HUMAN (4-242): 5.86e-81: 250: 18.81		H2B1J_HUMAN (1-127): 4.39e-54: 167: 85.04
+	Hs
		707727 NP1L4_HUMAN (4-242): 5.86e-81: 250: 18.81		H2B1B_HUMAN (1-127): 6.87e-54: 166: 85.83
+	Hs
		876845 NP1L1_HUMAN (2-278): 1.56e-83: 258: 18.13		H2B3B_HUMAN (1-127): 8.98e-51: 158: 85.83
+	Hs
		1282951 NP1L4_HUMAN (4-242): 5.86e-81: 250: 18.81		H2B1A_HUMAN (1-127): 1.72e-52: 163: 100.00
+	Hs
		1329387 TSYL2_HUMAN (34-273): 6.42e-73: 238: 32.08		U3KQK0_HUMAN (1-127): 1.53e-55: 172: 85.83
+	Hs
		1231232 NP1L4_HUMAN (4-242): 5.86e-81: 250: 18.81		H2B3B_HUMAN (1-127): 8.98e-51: 158: 85.83
+	Hs
		965383 TSPY1_HUMAN (22-250): 2.42e-77: 239: 33.19		H2B2E_HUMAN (1-127): 4.39e-54: 167: 85.83
+	Hs
		1307095 TSYL2_HUMAN (34-273): 6.42e-73: 238: 32.08		H2B1N_HUMAN (1-127): 1.22e-53: 166: 85.83
+	Rn
		961590 TSPY1_RAT (6-237): 1.91e-71: 225: 30.17		H2B1_RAT (1-127): 1e-50: 158: 81.89
+	Dm
		355275 Q9W1G7_DROME (18-238): 1.82e-67: 216: 20.54		H2B_DROME (37-127): 3.48e-47: 149: 94.51
+	Dm
		355262 Q24150_DROME (18-238): 2.14e-67: 215: 20.54		H2B_DROME (37-127): 3.48e-47: 149: 94.51
+	Sc
		355792 NAP1_YEAST (6-286): 9.91e-70: 223: 20.45		H2B2_YEAST (4-126): 4.46e-41: 134: 69.36