HitPredict

Interactor 1: SRSF2 (Q01130)
Serine/arginine-rich splicing factor 2 (Protein PR264) (Splicing component, 35 kDa) (Splicing factor SC35) (SC-35) (Splicing factor, arginine/serine-rich 2)
Gene: SRSF2

Interactor 2: LARP7 (Q4G0J3)
La-related protein 7 (La ribonucleoprotein domain family member 7) (hLARP7) (P-TEFb-interaction protein for 7SK stability) (PIP7S)
Gene: LARP7

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	1.00	0.618

Property	Details
Experiments	29845934
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	La~RRM_1, RRM_1~RRM_1
Common GO terms	GO:0003723 - RNA binding GO:0005634 - nucleus GO:0005654 - nucleoplasm GO:0005829 - cytosol GO:0006397 - mRNA processing and 1 others more... GO:0008380 - RNA splicing
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 221 Hs			1 582
+	Hs
		1073582 SF3B4_HUMAN (4-205): 1.41e-52: 176: 17.24		LARP7_HUMAN (1-582): 1.26e-127: 388: 100.00
+	Hs
		516541 PABP1_HUMAN (6-202): 1.69e-41: 150: 18.27		LARP7_HUMAN (1-582): 1.26e-127: 388: 100.00
+	Mm
		985649 SRSF2_MOUSE (1-221): 1.22e-43: 147: 100.00		LARP7_MOUSE (8-582): 1.3e-120: 370: 79.20
+	Hs
		516689 PABP1_HUMAN (6-202): 1.69e-41: 150: 18.27		PABP3_HUMAN (1-333): 6.27e-42: 162: 10.11
+	Hs
		516495 PABP1_HUMAN (6-202): 1.69e-41: 150: 18.27		PABP4_HUMAN (1-208): 8.15e-41: 158: 11.98
+	Hs
		516339 PABP1_HUMAN (6-202): 1.69e-41: 150: 18.27		PABP1_HUMAN (1-405): 1.94e-40: 157: 10.29
+	Hs
		516568 PABP1_HUMAN (6-202): 1.69e-41: 150: 18.27		LARP4_HUMAN (22-216): 3.23e-40: 157: 21.32
+	Hs
		516616 PABP1_HUMAN (6-202): 1.69e-41: 150: 18.27		LAR4B_HUMAN (2-216): 8.48e-36: 145: 17.02
+	Hs
		1020249 ELAV2_HUMAN (1-195): 6.01e-38: 136: 15.79		PABP4_HUMAN (1-208): 8.15e-41: 158: 11.98
+	Hs
		516484 ELAV2_HUMAN (1-195): 6.01e-38: 136: 15.79		PABP1_HUMAN (1-405): 1.94e-40: 157: 10.29
+	Hs
		1020300 ELAV2_HUMAN (1-195): 6.01e-38: 136: 15.79		LAR4B_HUMAN (2-216): 8.48e-36: 145: 17.02
+	Hs
		516635 PABP1_HUMAN (6-202): 1.69e-41: 150: 18.27		PABP5_HUMAN (12-206): 7.64e-32: 128: 14.15
+	Hs
		474019 ELAV2_HUMAN (1-195): 6.01e-38: 136: 15.79		PAB4L_HUMAN (1-203): 9.24e-35: 136: 11.85
+	Hs
		1020306 ELAV2_HUMAN (1-195): 6.01e-38: 136: 15.79		PABP5_HUMAN (12-206): 7.64e-32: 128: 14.15
+	Hs
		1268156 SRSF8_HUMAN (1-183): 4.13e-29: 111: 63.39		LAR4B_HUMAN (2-216): 8.48e-36: 145: 17.02
+	Mm
		665745 PABP1_MOUSE (6-202): 2.07e-41: 150: 18.27		TIA1_MOUSE (120-325): 5.06e-24: 106: 13.94
+	Mm
		857332 SRSF2_MOUSE (1-221): 1.22e-43: 147: 100.00		TIA1_MOUSE (120-325): 5.06e-24: 106: 13.94
+	Hs
		516561 PABP1_HUMAN (6-202): 1.69e-41: 150: 18.27		LARP1_HUMAN (29-114): 6.35e-13: 73.8: 40.23
+	Hs
		1020277 ELAV2_HUMAN (1-195): 6.01e-38: 136: 15.79		LARP1_HUMAN (29-114): 6.35e-13: 73.8: 40.23
+	Hs
		1020265 ELAV2_HUMAN (1-195): 6.01e-38: 136: 15.79		ELAV1_HUMAN (92-211): 7.72e-13: 71.9: 22.50