HitPredict

Interactor 1: FOXK2 (Q01167)
Forkhead box protein K2 (G/T-mismatch specific binding protein) (nGTBP) (Interleukin enhancer-binding factor 1)
Gene: FOXK2

Interactor 2: SP130 (Q9H0E3)
Histone deacetylase complex subunit SAP130 (130 kDa Sin3-associated polypeptide) (Sin3-associated polypeptide p130)
Gene: SAP130

Species: Homo sapiens

Source: intact

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.65	0.60	0.628

Property	Details
Experiments	25609649, 27773593
Identification Methods	affinity chromatography technology, biochemical, tandem affinity purification
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005634 - nucleus
Homologous interactions	10

Homologous interactions

Color coding for hit scores

	1 660 Hs			1 1048
+	Hs
		952871 FOXK1_HUMAN (34-627): 5.33e-81: 273: 53.57		SP130_HUMAN (1-1048): 2.19e-131: 426: 100.00
+	Hs
		964234 FOXK2_HUMAN (35-660): 2.35e-129: 397: 100.00		CIC_HUMAN (284-939): 3.09e-10: 67: 10.76
+	Hs
		952856 FOXK1_HUMAN (34-627): 5.33e-81: 273: 53.57		CIC_HUMAN (284-939): 3.09e-10: 67: 10.76
+	Hs
		1021235 FOXI1_HUMAN (134-513): 1.62e-56: 197: 23.42		KMT2C_HUMAN (364-832): 7.84e-09: 62.5: 15.83
+	Hs
		1021148 FOXC1_HUMAN (197-406): 2.04e-52: 191: 32.04		CIC_HUMAN (284-939): 3.09e-10: 67: 10.76
+	Hs
		1021338 FOXL1_HUMAN (233-411): 1.42e-53: 189: 34.90		CIC_HUMAN (284-939): 3.09e-10: 67: 10.76
+	Hs
		1021323 FOXL1_HUMAN (233-411): 1.42e-53: 189: 34.90		KMT2C_HUMAN (364-832): 7.84e-09: 62.5: 15.83
+	Dm
		970538 FD3_DROME (183-374): 5.49e-48: 176: 33.33		Q9VLS7_DROME (1-681): 4.35e-10: 66.2: 9.97
+	Hs
		1016221 FOXO1_HUMAN (118-660): 3.89e-44: 169: 16.00		TITIN_HUMAN (59-898): 8.03e-10: 65.5: 9.13
+	Hs
		877807 FOXA1_HUMAN (147-565): 2.65e-46: 172: 19.91		KMT2C_HUMAN (364-832): 7.84e-09: 62.5: 15.83