HitPredict

Interactor 1: SUMO2 (P61956)
Small ubiquitin-related modifier 2 (SUMO-2) (HSMT3) (SMT3 homolog 2) (SUMO-3) (Sentrin-2) (Ubiquitin-like protein SMT3B) (Smt3B)
Gene: SUMO2

Interactor 2: BRD3 (Q15059)
Bromodomain-containing protein 3 (RING3-like protein)
Gene: BRD3

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.479

Property	Details
Experiments	34349018
Identification Methods	cross-linking study
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005634 - nucleus GO:0045944 - positive regulation of transcription by RNA polymerase II
Homologous interactions	10

Homologous interactions

Color coding for hit scores

	1 95 Hs			1 726
+	Hs
		991331 SUMO1_HUMAN (1-93): 7.79e-35: 116: 45.36		BRD3_HUMAN (1-702): 1.03e-155: 470: 100.00
+	Hs
		259717 SUMO2_HUMAN (1-95): 3.58e-44: 139: 100.00		BRD4_HUMAN (3-644): 3.51e-104: 349: 52.55
+	Hs
		259694 SUMO3_HUMAN (1-94): 3.78e-41: 132: 96.81		BRD4_HUMAN (3-644): 3.51e-104: 349: 52.55
+	Hs
		259765 SUMO1_HUMAN (1-93): 7.79e-35: 116: 45.36		BRD4_HUMAN (3-644): 3.51e-104: 349: 52.55
+	Hs
		964509 SUMO2_HUMAN (1-95): 3.58e-44: 139: 100.00		ZMYD8_HUMAN (3-713): 1.39e-58: 217: 12.28
+	Hs
		964245 SUMO2_HUMAN (1-95): 3.58e-44: 139: 100.00		EP300_HUMAN (4-177): 1.06e-35: 148: 23.43
+	Hs
		939183 SUMO3_HUMAN (1-94): 3.78e-41: 132: 96.81		EP300_HUMAN (4-177): 1.06e-35: 148: 23.43
+	At
		1319717 Q8LCF9_ARATH (2-91): 5.3e-25: 94.7: 25.28		GTE2_ARATH (19-311): 2.47e-37: 149: 18.43
+	Hs
		964352 SUMO2_HUMAN (1-95): 3.58e-44: 139: 100.00		PB1_HUMAN (152-486): 2.23e-20: 99.1: 12.85
+	Hs
		639702 SUMO2_HUMAN (1-95): 3.58e-44: 139: 100.00		TAF1_HUMAN (20-303): 4.78e-19: 94.5: 13.73