HitPredict

Interactor 1: 1433G (P61981)
14-3-3 protein gamma (Protein kinase C inhibitor protein 1) (KCIP-1) [Cleaved into: 14-3-3 protein gamma, N-terminally processed]
Gene: YWHAG

Interactor 2: CGNL1 (Q0VF96)
Cingulin-like protein 1 (Junction-associated coiled-coil protein) (Paracingulin)
Gene: CGNL1

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.80	0.50	0.633

Property	Details
Experiments	33961781, 36931259, 20936779, 28514442
Identification Methods	affinity chromatography technology, proximity labelling technology, two hybrid, anti tag coimmunoprecipitation, two hybrid pooling approach
Interaction Type	physical association, direct interaction, association

Property	Details
Interacting Pfam domains	-
Common GO terms	-
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 247 Hs			1 1302
+	Hs
		773148 1433E_HUMAN (1-244): 2.03e-141: 398: 63.53		MYH10_HUMAN (137-1205): 7.97e-45: 180: 12.61
+	Hs
		773146 1433G_HUMAN (1-247): 3.17e-139: 392: 100.00		MYH10_HUMAN (137-1205): 7.97e-45: 180: 12.61
+	Hs
		971450 1433E_HUMAN (1-244): 2.03e-141: 398: 63.53		CGNL1_HUMAN (723-1302): 2.03e-29: 129: 14.65
+	Hs
		1049236 1433F_HUMAN (1-246): 2.51e-135: 382: 86.99		CGNL1_HUMAN (723-1302): 2.03e-29: 129: 14.65
+	Mm
		989976 1433Z_MOUSE (2-245): 8.5e-109: 315: 74.59		MYH10_MOUSE (137-1205): 9.37e-45: 180: 12.71
+	Hs
		776794 1433E_HUMAN (1-244): 2.03e-141: 398: 63.53		MYH11_HUMAN (82-702): 6.59e-19: 95.7: 10.75
+	Hs
		776805 1433F_HUMAN (1-246): 2.51e-135: 382: 86.99		MYH11_HUMAN (82-702): 6.59e-19: 95.7: 10.75
+	Hs
		972089 1433E_HUMAN (1-244): 2.03e-141: 398: 63.53		CING_HUMAN (356-748): 5.6e-09: 62.9: 12.47
+	Hs
		966972 1433G_HUMAN (1-247): 3.17e-139: 392: 100.00		CING_HUMAN (356-748): 5.6e-09: 62.9: 12.47
+	Hs
		729781 1433B_HUMAN (2-247): 1.92e-109: 317: 75.40		CGNL1_HUMAN (723-1302): 2.03e-29: 129: 14.65
+	Hs
		1049865 1433F_HUMAN (1-246): 2.51e-135: 382: 86.99		CING_HUMAN (356-748): 5.6e-09: 62.9: 12.47
+	Hs
		990150 1433Z_HUMAN (2-245): 2.4e-108: 314: 74.59		CGNL1_HUMAN (723-1302): 2.03e-29: 129: 14.65
+	Mm
		990028 1433Z_MOUSE (2-245): 8.5e-109: 315: 74.59		MYH9_MOUSE (94-861): 3.54e-27: 122: 9.33
+	Hs
		772728 1433Z_HUMAN (2-245): 2.4e-108: 314: 74.59		MYH9_HUMAN (94-864): 1.71e-25: 117: 7.91
+	Hs
		535929 1433Z_HUMAN (2-245): 2.4e-108: 314: 74.59		MYH3_HUMAN (72-840): 1.37e-22: 107: 10.80
+	Hs
		556912 1433Z_HUMAN (2-245): 2.4e-108: 314: 74.59		MYH7_HUMAN (59-840): 4.1e-22: 106: 11.00
+	Hs
		990855 1433Z_HUMAN (2-245): 2.4e-108: 314: 74.59		MYH2_HUMAN (87-816): 1.7e-19: 97.6: 8.11
+	Hs
		776800 1433Z_HUMAN (2-245): 2.4e-108: 314: 74.59		MYH11_HUMAN (82-702): 6.59e-19: 95.7: 10.75
+	Hs
		730315 1433B_HUMAN (2-247): 1.92e-109: 317: 75.40		CING_HUMAN (356-748): 5.6e-09: 62.9: 12.47
+	Hs
		990823 1433Z_HUMAN (2-245): 2.4e-108: 314: 74.59		CING_HUMAN (356-748): 5.6e-09: 62.9: 12.47