Interactor 1: EXOSX (Q01780)
Exosome complex component 10 (EC 3.1.13.-) (Autoantigen PM/Scl 2) (P100 polymyositis-scleroderma overlap syndrome-associated autoantigen) (Polymyositis/scleroderma autoantigen 100 kDa) (PM/Scl-100) (Polymyositis/scleroderma autoantigen 2)
Gene: EXOSC10

Interactor 2: XRN2 (Q9H0D6)
5'-3' exoribonuclease 2 (EC 3.1.13.-) (DHM1-like protein) (DHP protein)
Gene: XRN2

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score Annotation score Interaction score
0.43 0.60 0.508

The method score is based on:

Property Details
Experiments 15231747
Identification Methods two hybrid
Interaction Type direct interaction, physical association

The annotation score is based on:

Property Details
Interacting Pfam domains -
Common GO terms GO:0000175 - 3'-5'-RNA exonuclease activity
GO:0000956 - nuclear-transcribed mRNA catabolic process
GO:0003723 - RNA binding
GO:0005634 - nucleus
GO:0005654 - nucleoplasm
and 6 others

more...

Homologous interactions 2

Homologous interactions

Color coding for hit scores

1 885
Hs

1 950
+ Hs
+ Sp

Service provided by Combinatics, Japan

Last updated: 15 Jul 2024