Protein: F117B
Protein FAM117B (Amyotrophic lateral sclerosis 2 chromosomal region candidate gene 13 protein)

Gene: F117B, FAM117B
Organism: Homo sapiens
Interactions: 54
UniProt ID: Q6P1L5

Gene Ontology (top 5):

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

991578

DYL1
Dynein light chain 1, cytoplasmic

8

5

High-throughput

0.687

High

1115735

DYR1A
Dual specificity tyrosine-phosphorylation-regulated kinase 1A

7

5

High-throughput

0.685

High

1240805

DYL2
Dynein light chain 2, cytoplasmic

6

5

High-throughput

0.668

High

1121423

KEAP1
Kelch-like ECH-associated protein 1

5

1

Small-scale

0.661

High

1240813

DYR1B
Dual specificity tyrosine-phosphorylation-regulated kinase 1B

4

5

High-throughput

0.643

High

966476

1433G
14-3-3 protein gamma

4

16

High-throughput

0.638

High

1049429

1433F
14-3-3 protein eta

4

16

High-throughput

0.638

High

729953

1433B
14-3-3 protein beta/alpha

4

16

High-throughput

0.619

High

964643

DCAF7
DDB1- and CUL4-associated factor 7

3

1

High-throughput

0.616

High

691134

1433T
14-3-3 protein theta

3

16

High-throughput

0.593

High

990362

1433Z
14-3-3 protein zeta/delta

3

16

High-throughput

0.593

High

971652

1433E
14-3-3 protein epsilon

3

1

High-throughput

0.578

High

273268

T22D2
TSC22 domain family protein 2

2

1

High-throughput

0.574

High

332414

TNKS1
Poly [ADP-ribose] polymerase tankyrase-1

2

1

High-throughput

0.574

High

1240807

T22D3
TSC22 domain family protein 3

2

1

High-throughput

0.574

High

1240808

TNKS2
Poly [ADP-ribose] polymerase tankyrase-2

2

1

High-throughput

0.574

High

730682

1433S
14-3-3 protein sigma

2

16

High-throughput

0.533

High

706171

S10A2
Protein S100-A2

1

1

High-throughput

0.489

High

1113412

CUL3
Cullin-3

1

1

High-throughput

0.437

High

1199521

KLH22
Kelch-like protein 22

1

1

High-throughput

0.407

High

1240803

BANP
Protein BANP

4

0

High-throughput

0.364

High

610378

PRS6A
26S proteasome regulatory subunit 6A

3

0

High-throughput

0.347

High

881714

FNTB
Protein farnesyltransferase subunit beta

3

0

High-throughput

0.347

High

156294

G3PT
Glyceraldehyde-3-phosphate dehydrogenase, testis-specific

2

0

High-throughput

0.328

High

881667

FNTA
Protein farnesyltransferase/geranylgeranyltransferase type-1 subunit alpha

2

0

High-throughput

0.328

High

1240801

A16A1
Aldehyde dehydrogenase family 16 member A1

2

0

High-throughput

0.328

High

1240806

IMP1L
Mitochondrial inner membrane protease subunit 1

2

0

High-throughput

0.328

High

1240809

NRBP
Nuclear receptor-binding protein

2

0

High-throughput

0.328

High

1240810

PNMA2
Paraneoplastic antigen Ma2

2

0

High-throughput

0.328

High

353392

AGR2
Anterior gradient protein 2 homolog

2

0

High-throughput

0.316

High

827820

STAT3
Signal transducer and activator of transcription 3

2

0

High-throughput

0.310

High

369058

ASSY
Argininosuccinate synthase

1

0

High-throughput

0.279

Low

764838

CTNB1
Catenin beta-1

1

0

High-throughput

0.279

Low

1217866

BRE1A
E3 ubiquitin-protein ligase BRE1A

1

0

High-throughput

0.279

Low

167290

KLF11
Krueppel-like factor 11

1

0

High-throughput

0.268

Low

242021

PRKN
E3 ubiquitin-protein ligase parkin

1

0

High-throughput

0.268

Low

245986

KIF1B
Kinesin-like protein KIF1B

1

0

High-throughput

0.268

Low

274629

DNJB6
DnaJ homolog subfamily B member 6

1

0

High-throughput

0.268

Low

301490

WFS1
Wolframin

1

0

High-throughput

0.268

Low

415649

HSPB1
Heat shock protein beta-1

1

0

High-throughput

0.268

Low

637575

FLNA
Filamin-A

1

0

High-throughput

0.268

Low

665617

AT5F1
ATP synthase peripheral stalk subunit b, mitochondrial

1

0

High-throughput

0.268

Low

724763

METK2
S-adenosylmethionine synthase isoform type-2

1

0

High-throughput

0.268

Low

856746

BAG6
Large proline-rich protein BAG6

1

0

High-throughput

0.268

Low

954506

PRPS1
Ribose-phosphate pyrophosphokinase 1

1

0

High-throughput

0.268

Low

1005528

GPC5
Glypican-5 [Cleaved into: Secreted glypican-5]

1

0

High-throughput

0.268

Low

1031911

NC2B
Protein Dr1

1

0

High-throughput

0.268

Low

1096052

TADBP
TAR DNA-binding protein 43

1

0

High-throughput

0.268

Low

1240802

PIAS4
E3 SUMO-protein ligase PIAS4

1

0

High-throughput

0.268

Low

1240811

ICAM5
Intercellular adhesion molecule 5

1

0

High-throughput

0.268

Low

1240812

RNF11
RING finger protein 11

1

0

High-throughput

0.268

Low

1240814

TF3C3
General transcription factor 3C polypeptide 3

1

0

High-throughput

0.268

Low

1240804

NEDD1
Protein NEDD1

1

0

High-throughput

0.249

Low

372321

MYC
Myc proto-oncogene protein

1

0

High-throughput

0.232

Low


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Last updated: 11Aug2025