HitPredict

Interactor 1: XPC (Q01831)
DNA repair protein complementing XP-C cells (Xeroderma pigmentosum group C-complementing protein) (p125)
Gene: XPC

Interactor 2: H2AW (Q9P0M6)
Core histone macro-H2A.2 (Histone macroH2A2) (mH2A2)
Gene: MACROH2A2

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.65	0.60	0.628

Property	Details
Experiments	28514442, 33961781
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0000785 - chromatin GO:0005634 - nucleus GO:0005654 - nucleoplasm
Homologous interactions	8

Homologous interactions

Color coding for hit scores

	1 940 Hs			1 372
+	Hs
		260847 XPC_HUMAN (1-940): 0: 1158: 100.00		H2AY_HUMAN (1-371): 8.19e-156: 444: 66.31
+	Hs
		967072 XPC_HUMAN (1-940): 0: 1158: 100.00		MACD1_HUMAN (167-371): 4.34e-68: 219: 19.71
+	Hs
		555418 XPC_HUMAN (1-940): 0: 1158: 100.00		H2AX_HUMAN (1-144): 1.72e-66: 208: 57.14
+	Hs
		967049 XPC_HUMAN (1-940): 0: 1158: 100.00		H2A2B_HUMAN (1-123): 1.24e-64: 203: 63.49
+	Hs
		391659 XPC_HUMAN (1-940): 0: 1158: 100.00		H2A1B_HUMAN (1-126): 6.65e-64: 201: 60.47
+	Hs
		470354 XPC_HUMAN (1-940): 0: 1158: 100.00		H2A1_HUMAN (1-126): 6.37e-64: 201: 60.47
+	Hs
		967036 XPC_HUMAN (1-940): 0: 1158: 100.00		H2A2C_HUMAN (1-126): 7.57e-64: 201: 61.24
+	Hs
		967041 XPC_HUMAN (1-940): 0: 1158: 100.00		H2A2A_HUMAN (1-126): 4.27e-64: 201: 62.02