HitPredict

Interactor 1: OCRL (Q01968)
Inositol polyphosphate 5-phosphatase OCRL (EC 3.1.3.36) (EC 3.1.3.56) (Inositol polyphosphate 5-phosphatase OCRL-1) (OCRL-1) (Lowe oculocerebrorenal syndrome protein) (Phosphatidylinositol 3,4,5-triphosphate 5-phosphatase) (EC 3.1.3.86)
Gene: OCRL

Interactor 2: RAB35 (Q15286)
Ras-related protein Rab-35 (GTP-binding protein RAY) (Ras-related protein Rab-1C)
Gene: RAB35

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	1.00	0.618

Property	Details
Experiments	34079125
Identification Methods	proximity labelling technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	Ras~RhoGAP
Common GO terms	GO:0005829 - cytosol GO:0005886 - plasma membrane GO:0005905 - clathrin-coated pit
Homologous interactions	10

Homologous interactions

Color coding for hit scores

	1 901 Hs			1 201
+	Hs
		918850 OCRL_HUMAN (1-901): 0: 1075: 100.00		RAB1A_HUMAN (1-201): 5.61e-88: 258: 53.96
+	Hs
		968218 OCRL_HUMAN (1-901): 0: 1075: 100.00		RAB1B_HUMAN (1-201): 6.61e-86: 253: 53.96
+	Hs
		968196 OCRL_HUMAN (1-901): 0: 1075: 100.00		RAB1C_HUMAN (1-201): 8.38e-83: 245: 51.98
+	Hs
		894724 OCRL_HUMAN (1-901): 0: 1075: 100.00		RAB8A_HUMAN (1-199): 3.16e-82: 244: 46.00
+	Hs
		914016 OCRL_HUMAN (1-901): 0: 1075: 100.00		RB11A_HUMAN (2-201): 1.19e-79: 238: 40.67
+	Rn
		1157320 R9PXS2_RAT (14-901): 0: 1038: 93.81		RAB1A_RAT (1-201): 5.61e-88: 258: 53.96
+	Rn
		722753 R9PXS2_RAT (14-901): 0: 1038: 93.81		RAB8A_RAT (1-199): 8.96e-81: 240: 45.50
+	Hs
		845848 OCRL_HUMAN (1-901): 0: 1075: 100.00		RAB13_HUMAN (1-169): 1.35e-62: 194: 55.29
+	Hs
		685333 I5P2_HUMAN (143-897): 0: 719: 50.27		RAB8A_HUMAN (1-199): 3.16e-82: 244: 46.00
+	Dm
		185463 O46094_DROME (209-900): 1.12e-177: 537: 33.15		O18332_DROME (2-201): 3.07e-83: 247: 53.23