HitPredict

Interactor 1: TAGL (Q01995)
Transgelin (22 kDa actin-binding protein) (Protein WS3-10) (Smooth muscle protein 22-alpha) (SM22-alpha)
Gene: TAGLN

Interactor 2: SPTN1 (Q13813)
Spectrin alpha chain, non-erythrocytic 1 (Alpha-II spectrin) (Fodrin alpha chain) (Spectrin, non-erythroid alpha subunit)
Gene: SPTAN1

Species: Homo sapiens

Source: mint

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.33	1.00	0.575

Property	Details
Experiments	32774160
Identification Methods	anti tag coimmunoprecipitation
Interaction Type	association

Property	Details
Interacting Pfam domains	CH~EF-hand_7, CH~EFhand_Ca_insen, CH~Spectrin
Common GO terms	GO:0051015 - actin filament binding
Homologous interactions	9

Homologous interactions

Color coding for hit scores

	1 201 Hs			1 2472
+	Hs
		809302 IQGA1_HUMAN (4-183): 1.85e-45: 162: 18.28		SPTN1_HUMAN (1-2472): 0: 714: 100.00
+	Hs
		963295 TAGL_HUMAN (1-201): 1.6e-89: 262: 100.00		SPTB2_HUMAN (2-1043): 1.4e-42: 174: 20.52
+	Hs
		164580 IQGA1_HUMAN (4-183): 1.85e-45: 162: 18.28		SPTN2_HUMAN (141-1932): 1.25e-65: 250: 20.41
+	Hs
		809270 IQGA1_HUMAN (4-183): 1.85e-45: 162: 18.28		SPTB2_HUMAN (2-1043): 1.4e-42: 174: 20.52
+	Hs
		809274 IQGA1_HUMAN (4-183): 1.85e-45: 162: 18.28		DYST_HUMAN (5-2410): 1.41e-35: 152: 10.59
+	Hs
		809312 IQGA1_HUMAN (4-183): 1.85e-45: 162: 18.28		PLEC_HUMAN (16-1253): 4.4e-31: 137: 9.18
+	Hs
		521494 IQGA1_HUMAN (4-183): 1.85e-45: 162: 18.28		ACTN1_HUMAN (1862-2210): 3.16e-11: 71.2: 22.25
+	Hs
		211526 IQGA1_HUMAN (4-183): 1.85e-45: 162: 18.28		ACTN4_HUMAN (1843-2219): 1.15e-09: 66.2: 20.15
+	Hs
		211626 LMO7_HUMAN (34-154): 2.25e-28: 113: 24.06		ACTN4_HUMAN (1843-2219): 1.15e-09: 66.2: 20.15