Protein: EFHD1
EF-hand domain-containing protein D1 (EF-hand domain-containing protein 1) (Swiprosin-2)

Gene: EFHD1
Organism: Homo sapiens
Interactions: 71
UniProt ID: Q9BUP0

Gene Ontology (top 5):
GO:0005509 - calcium ion binding
GO:0005739 - mitochondrion
GO:0005743 - mitochondrial inner membrane
GO:0031175 - neuron projection development
GO:0061891 - calcium ion sensor activity

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

1253289

CC141
Coiled-coil domain-containing protein 141

1

10

High-throughput

0.618

High

1406178

PMYT1
Membrane-associated tyrosine- and threonine-specific cdc2-inhibitory kinase

1

20

High-throughput

0.618

High

1413718

FSD1
Fibronectin type III and SPRY domain-containing protein 1

3

3

High-throughput

0.609

High

424259

S10A8
Protein S100-A8

2

0

High-throughput

0.602

High

396848

ESR1
Estrogen receptor

3

5

High-throughput

0.593

High

516581

CALM3
Calmodulin-3

1

17

High-throughput

0.575

High

190089

FOXP2
Forkhead box protein P2

2

1

High-throughput

0.574

High

406926

MAS
Proto-oncogene Mas

2

2

High-throughput

0.574

High

1414534

DUS10
Dual specificity protein phosphatase 10

2

3

High-throughput

0.574

High

336235

ZIC2
Zinc finger protein ZIC 2

2

2

High-throughput

0.558

High

953066

ACTB
Actin, cytoplasmic 1

1

3

High-throughput

0.553

High

1146468

KS6A2
Ribosomal protein S6 kinase alpha-2

1

2

High-throughput

0.553

High

301817

ANXA9
Annexin A9

1

2

High-throughput

0.536

High

582936

EZRI
Ezrin

2

1

High-throughput

0.533

High

1059055

TRHY
Trichohyalin

1

7

High-throughput

0.515

High

1393352

OXND1
Oxidoreductase NAD-binding domain-containing protein 1

1

0

High-throughput

0.513

High

516242

PAL4G
Peptidyl-prolyl cis-trans isomerase A-like 4G

2

4

High-throughput

0.504

High

66965

FIGL2
Fidgetin-like protein 2

1

3

High-throughput

0.489

High

835373

VIPR2
Vasoactive intestinal polypeptide receptor 2

1

1

High-throughput

0.489

High

866806

CAZA2
F-actin-capping protein subunit alpha-2

1

4

High-throughput

0.489

High

1052096

CALD1
Caldesmon

1

10

High-throughput

0.489

High

1124704

SRC8
Src substrate cortactin

1

7

High-throughput

0.489

High

1216309

MTCL3
Microtubule cross-linking factor 3

1

14

High-throughput

0.489

High

1218894

TAF3
Transcription initiation factor TFIID subunit 3

1

1

High-throughput

0.489

High

1230342

K1C39
Keratin, type I cytoskeletal 39

1

2

High-throughput

0.489

High

1272768

G2E3
G2/M phase-specific E3 ubiquitin-protein ligase

1

1

High-throughput

0.489

High

1308695

FMNL3
Formin-like protein 3

1

4

High-throughput

0.489

High

1387190

RB39B
Ras-related protein Rab-39B

1

3

High-throughput

0.489

High

1414528

ZN492
Zinc finger protein 492

1

1

High-throughput

0.489

High

1414531

PLAL2
Zinc finger protein PLAGL2

1

3

High-throughput

0.489

High

1414532

CE164
Centrosomal protein of 164 kDa

1

13

High-throughput

0.489

High

890048

PSN1
Presenilin-1

1

0

High-throughput

0.486

High

535476

BIP
Endoplasmic reticulum chaperone BiP

1

5

High-throughput

0.479

High

1280459

HUWE1
E3 ubiquitin-protein ligase HUWE1

1

1

High-throughput

0.479

High

1367159

ESR2
Estrogen receptor beta

1

5

High-throughput

0.479

High

1385423

EFHD2
EF-hand domain-containing protein D2

1

15

High-throughput

0.479

High

1414530

CLC4E
C-type lectin domain family 4 member E

1

4

High-throughput

0.479

High

560502

IFM1
Interferon-induced transmembrane protein 1

1

2

High-throughput

0.470

High

1127676

KT33B
Keratin, type I cuticular Ha3-II

1

1

High-throughput

0.470

High

1361698

CHC10
Coiled-coil-helix-coiled-coil-helix domain-containing protein 10, mitochondrial

1

0

High-throughput

0.458

High

164430

NRP1
Neuropilin-1

1

1

High-throughput

0.437

High

188986

TMPS2
Transmembrane protease serine 2

1

3

High-throughput

0.437

High

323556

TRI37
E3 ubiquitin-protein ligase TRIM37

1

2

High-throughput

0.437

High

373027

MYC
Myc proto-oncogene protein

1

5

High-throughput

0.437

High

390745

TFR1
Transferrin receptor protein 1

1

1

High-throughput

0.437

High

459331

CATL1
Procathepsin L

1

3

High-throughput

0.437

High

930039

UBP14
Ubiquitin carboxyl-terminal hydrolase 14

1

4

High-throughput

0.437

High

1140778

KIF14
Kinesin-like protein KIF14

1

7

High-throughput

0.437

High

1197556

PAN2
PAN2-PAN3 deadenylation complex catalytic subunit PAN2

1

3

High-throughput

0.437

High

1218651

OTU1
Ubiquitin thioesterase OTU1

1

1

High-throughput

0.437

High

1293812

FBX11
F-box only protein 11

1

4

High-throughput

0.437

High

1358104

NUDC2
NudC domain-containing protein 2

1

1

High-throughput

0.437

High

1360926

CLC4D
C-type lectin domain family 4 member D

1

4

High-throughput

0.437

High

1414524

ACE2
Angiotensin-converting enzyme 2

1

1

High-throughput

0.437

High

1414525

RNF12
E3 ubiquitin-protein ligase RLIM

1

6

High-throughput

0.437

High

1414526

LUZP4
Leucine zipper protein 4

1

1

Small-scale

0.437

High

1414529

ZO2
Tight junction protein 2

1

3

High-throughput

0.437

High

1103357

CTBP1
C-terminal-binding protein 1

1

3

High-throughput

0.407

High

1281192

CPLX4
Complexin-4

2

0

High-throughput

0.328

High

429135

7B2
Neuroendocrine protein 7B2

1

0

High-throughput

0.279

Low

611965

RL35A
Large ribosomal subunit protein eL33

1

0

High-throughput

0.279

Low

1040619

PO3F1
POU domain, class 3, transcription factor 1

1

0

High-throughput

0.279

Low

1214858

ARM12
Armadillo repeat-containing protein 12

1

0

High-throughput

0.279

Low

1413145

SPXN
Spexin

1

0

High-throughput

0.279

Low

1414527

OR1A1
Olfactory receptor 1A1

1

0

High-throughput

0.279

Low

1414533

EXC6B
Exocyst complex component 6B

1

0

High-throughput

0.279

Low

130225

PGRC1
Membrane-associated progesterone receptor component 1

1

0

High-throughput

0.269

Low

352537

TOP3B
DNA topoisomerase 3-beta-1

1

0

High-throughput

0.269

Low

1348151

NDNF
Protein NDNF

1

0

High-throughput

0.269

Low

409485

HLAA
HLA class I histocompatibility antigen, A alpha chain

1

0

High-throughput

0.249

Low

971010

UBE2H
Ubiquitin-conjugating enzyme E2 H

1

0

High-throughput

0.249

Low


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Last updated: 11Aug2025