Interactor 1: GCYB1 (Q02153)
Guanylate cyclase soluble subunit beta-1 (GCS-beta-1) (EC 4.6.1.2) (Guanylate cyclase soluble subunit beta-3) (GCS-beta-3) (Soluble guanylate cyclase small subunit)
Gene: GUCY1B1

Interactor 2: GCYB1 (Q02153)
Guanylate cyclase soluble subunit beta-1 (GCS-beta-1) (EC 4.6.1.2) (Guanylate cyclase soluble subunit beta-3) (GCS-beta-3) (Soluble guanylate cyclase small subunit)
Gene: GUCY1B1

Species: Homo sapiens

Source: intact

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.41 1.00 0.647

The method score is based on:

Property Details
Experiments 23505436
Identification Methods x-ray crystallography
Interaction Type direct interaction

The annotation score is based on:

Property Details
Interacting Pfam domains Guanylate_cyc~Guanylate_cyc, Guanylate_cyc~HNOBA, HNOB~HNOB, HNOB~HNOBA, HNOBA~HNOBA
Common GO terms GO:0004016 - adenylate cyclase activity
GO:0004383 - guanylate cyclase activity
GO:0005525 - GTP binding
GO:0005829 - cytosol
GO:0006182 - cGMP biosynthetic process
and 16 others

more...

Homologous interactions 8

Homologous interactions

Color coding for hit scores

1 619
Hs

1 619
+ Hs
+ Hs
+ Dm
+ Hs
+ Mm
+ Hs
+ Hs
+ Hs

Service provided by Combinatics, Japan

Last updated: 15 Jul 2024