HitPredict

Interactor 1: NU100 (Q02629)
Nucleoporin NUP100/NSP100 (Nuclear pore protein NUP100/NSP100)
Gene: NUP100

Interactor 2: MEX67 (Q99257)
mRNA export factor MEX67
Gene: MEX67

Species: Saccharomyces cerevisiae S288C

Source: intact

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.87	0.60	0.725

Property	Details
Experiments	11387327, 33226341, 12543930, 11104765, 23212245, 18046405
Identification Methods	affinity chromatography technology, pull down
Interaction Type	physical association, direct interaction

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0003723 - RNA binding GO:0005643 - nuclear pore GO:0006406 - mRNA export from nucleus
Homologous interactions	18

Homologous interactions

Color coding for hit scores

	1 959 Sc			1 599
+	Hs
		1017095 TROP_HUMAN (4-570): 2.92e-34: 144: 14.19		NXF2_HUMAN (10-598): 3e-180: 525: 18.15
+	Hs
		858064 NUP98_HUMAN (8-689): 1.9e-28: 125: 15.05		NXF1_HUMAN (14-598): 0: 540: 19.93
+	Hs
		72771 B4DET5_HUMAN (37-709): 1.07e-22: 106: 11.10		NXF1_HUMAN (14-598): 0: 540: 19.93
+	Hs
		727326 NU214_HUMAN (80-796): 4.91e-17: 88.9: 10.43		NXF1_HUMAN (14-598): 0: 540: 19.93
+	Hs
		834680 NU153_HUMAN (18-558): 4.59e-17: 88.9: 12.20		NXF1_HUMAN (14-598): 0: 540: 19.93
+	Hs
		1293163 P121A_HUMAN (5-659): 1.27e-16: 87.3: 10.42		NXF1_HUMAN (14-598): 0: 540: 19.93
+	Sc
		774387 NU159_YEAST (236-794): 8.24e-27: 120: 11.19		MEX67_YEAST (1-599): 1.91e-171: 501: 100.00
+	Hs
		231346 GANP_HUMAN (4-261): 2.5e-14: 79.9: 19.62		NXF1_HUMAN (14-598): 0: 540: 19.93
+	Hs
		727313 NU214_HUMAN (80-796): 4.91e-17: 88.9: 10.43		NXF2_HUMAN (10-598): 3e-180: 525: 18.15
+	Hs
		834667 NU153_HUMAN (18-558): 4.59e-17: 88.9: 12.20		NXF2_HUMAN (10-598): 3e-180: 525: 18.15
+	Sc
		971930 NU116_YEAST (1-815): 1.7e-21: 103: 15.12		MEX67_YEAST (1-599): 1.91e-171: 501: 100.00
+	Sc
		830687 NU145_YEAST (151-514): 8.4e-21: 100: 20.06		MEX67_YEAST (1-599): 1.91e-171: 501: 100.00
+	Sc
		541937 NSP1_YEAST (1-496): 6.13e-14: 78.5: 13.58		MEX67_YEAST (1-599): 1.91e-171: 501: 100.00
+	Sc
		823015 NUP57_YEAST (281-544): 4.23e-13: 74.9: 26.42		MEX67_YEAST (1-599): 1.91e-171: 501: 100.00
+	Sc
		830663 NUP42_YEAST (413-807): 3.6e-09: 62.3: 11.53		MEX67_YEAST (1-599): 1.91e-171: 501: 100.00
+	Tt
		101905 NU145_CHATD (7-955): 6.86e-57: 216: 19.90		G0SET4_CHATD (14-597): 2.6e-105: 333: 25.80
+	Dm
		1353486 NU214_DROME (4-787): 2.76e-16: 86.6: 8.51		NXF1_DROME (21-598): 9.29e-140: 423: 21.42
+	Dm
		1370263 Q9VLS7_DROME (118-826): 2.74e-35: 148: 12.81		Q9VQV7_DROME (119-557): 2.45e-67: 235: 15.85