HitPredict

Interactor 1: NU116 (Q02630)
Nucleoporin NUP116/NSP116 (Nuclear pore protein NUP116/NSP116)
Gene: NUP116

Interactor 2: IMA1 (Q02821)
Importin subunit alpha (Karyopherin subunit alpha) (Karyopherin-60) (Serine-rich RNA polymerase I suppressor protein)
Gene: SRP1

Species: Saccharomyces cerevisiae S288C

Source: biogrid

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.54	0.60	0.571

Property	Details
Experiments	11387327, 10684247
Identification Methods	affinity chromatography technology, biochemical
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005635 - nuclear envelope GO:0006606 - protein import into nucleus GO:0008139 - nuclear localization sequence binding
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 1113 Sc			1 542
+	Sc
		971868 NU100_YEAST (1-708): 2.45e-22: 106: 16.36		IMA1_YEAST (1-542): 2.38e-161: 471: 100.00
+	Sp
		293244 NU124_SCHPO (3-494): 1.04e-17: 91.2: 9.83		IMA2_SCHPO (8-542): 1.03e-146: 434: 56.43
+	Dm
		1359634 Q9VGL0_DROME (28-673): 2.66e-28: 125: 12.09		Q9V455_DROME (13-541): 1.51e-133: 399: 43.26
+	Hs
		72691 B4DET5_HUMAN (4-683): 7.76e-20: 97.7: 9.66		IMA3_HUMAN (8-541): 2.87e-143: 424: 45.07
+	Hs
		72690 B4DET5_HUMAN (4-683): 7.76e-20: 97.7: 9.66		IMA4_HUMAN (8-541): 4.18e-142: 421: 44.90
+	Hs
		72719 B4DET5_HUMAN (4-683): 7.76e-20: 97.7: 9.66		IMA1_HUMAN (6-541): 1.45e-141: 420: 44.02
+	Hs
		131388 NU214_HUMAN (4-549): 7.13e-15: 82.3: 14.91		IMA4_HUMAN (8-541): 4.18e-142: 421: 44.90
+	Hs
		238723 P121A_HUMAN (1-464): 2.06e-13: 77.3: 13.76		IMA7_HUMAN (6-541): 1.46e-143: 426: 50.37
+	Hs
		65034 P121C_HUMAN (1-464): 1.28e-13: 77.7: 14.56		IMA3_HUMAN (8-541): 2.87e-143: 424: 45.07
+	Hs
		134948 P121A_HUMAN (1-464): 2.06e-13: 77.3: 13.76		IMA3_HUMAN (8-541): 2.87e-143: 424: 45.07
+	Hs
		65033 P121C_HUMAN (1-464): 1.28e-13: 77.7: 14.56		IMA4_HUMAN (8-541): 4.18e-142: 421: 44.90
+	Hs
		131490 P121A_HUMAN (1-464): 2.06e-13: 77.3: 13.76		IMA4_HUMAN (8-541): 4.18e-142: 421: 44.90
+	Hs
		65040 P121C_HUMAN (1-464): 1.28e-13: 77.7: 14.56		IMA1_HUMAN (6-541): 1.45e-141: 420: 44.02
+	Hs
		853423 P121A_HUMAN (1-464): 2.06e-13: 77.3: 13.76		IMA1_HUMAN (6-541): 1.45e-141: 420: 44.02
+	Hs
		238649 NU153_HUMAN (5-423): 1.86e-10: 67.7: 12.56		IMA7_HUMAN (6-541): 1.46e-143: 426: 50.37
+	Hs
		134853 NU153_HUMAN (5-423): 1.86e-10: 67.7: 12.56		IMA3_HUMAN (8-541): 2.87e-143: 424: 45.07
+	Hs
		131403 NU153_HUMAN (5-423): 1.86e-10: 67.7: 12.56		IMA4_HUMAN (8-541): 4.18e-142: 421: 44.90
+	Hs
		834565 NU153_HUMAN (5-423): 1.86e-10: 67.7: 12.56		IMA1_HUMAN (6-541): 1.45e-141: 420: 44.02
+	Hs
		168626 NU153_HUMAN (5-423): 1.86e-10: 67.7: 12.56		IMA6_HUMAN (6-541): 4.04e-136: 407: 49.35
+	Hs
		834566 NU153_HUMAN (5-423): 1.86e-10: 67.7: 12.56		IMA5_HUMAN (8-541): 1.74e-135: 405: 48.61