HitPredict

Interactor 1: 1433E (P62258)
14-3-3 protein epsilon (14-3-3E)
Gene: YWHAE

Interactor 2: LRCH1 (Q9Y2L9)
Leucine-rich repeat and calponin homology domain-containing protein 1 (Calponin homology domain-containing protein 1) (Neuronal protein 81) (NP81)
Gene: LRCH1

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.70	0.60	0.650

Property	Details
Experiments	31980649, 35271311, unassigned2173
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005737 - cytoplasm
Homologous interactions	10

Homologous interactions

Color coding for hit scores

	1 255 Hs			1 728
+	Hs
		972139 1433E_HUMAN (1-255): 4.89e-154: 430: 100.00		SHOC2_HUMAN (61-309): 1.18e-41: 162: 21.52
+	At
		1030928 14332_ARATH (4-255): 1.05e-147: 414: 74.41		BRL2_ARATH (240-658): 4.98e-37: 151: 10.23
+	At
		840545 14333_ARATH (1-253): 3.47e-147: 413: 74.12		BRL2_ARATH (240-658): 4.98e-37: 151: 10.23
+	Mm
		972215 1433E_MOUSE (1-255): 4.89e-154: 430: 100.00		LRCH2_MOUSE (4-258): 7.25e-30: 128: 22.22
+	Hs
		971910 1433E_HUMAN (1-255): 4.89e-154: 430: 100.00		ERBIN_HUMAN (43-199): 3.28e-26: 117: 22.79
+	At
		1030922 14332_ARATH (4-255): 1.05e-147: 414: 74.41		CLV1_ARATH (1-278): 1.57e-30: 130: 19.37
+	Mm
		972269 1433E_MOUSE (1-255): 4.89e-154: 430: 100.00		LRCH3_MOUSE (6-163): 5.71e-18: 90.5: 16.88
+	At
		840502 14333_ARATH (1-253): 3.47e-147: 413: 74.12		EMS1_ARATH (2-163): 5.38e-18: 90.9: 21.34
+	At
		840304 14331_ARATH (4-245): 3.9e-144: 405: 75.41		EMS1_ARATH (2-163): 5.38e-18: 90.9: 21.34
+	Zm
		22653 B6U284_MAIZE (3-255): 8.26e-147: 412: 70.59		A0A1D6I257_MAIZE (489-640): 1.65e-11: 70.1: 11.84