HitPredict

Interactor 1: MP2K1 (Q02750)
Dual specificity mitogen-activated protein kinase kinase 1 (MAP kinase kinase 1) (MAPKK 1) (MKK1) (EC 2.7.12.2) (ERK activator kinase 1) (MAPK/ERK kinase 1) (MEK 1)
Gene: MAP2K1

Interactor 2: TRI67 (Q6ZTA4)
Tripartite motif-containing protein 67 (TRIM9-like protein)
Gene: TRIM67

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.80	0.553

Property	Details
Experiments	36215168
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	Pkinase~fn3
Common GO terms	-
Homologous interactions	18

Homologous interactions

Color coding for hit scores

	1 393 Hs			1 783
+	Hs
		647914 MARK3_HUMAN (1-352): 4.84e-120: 366: 19.72		TRI67_HUMAN (1-783): 0: 593: 100.00
+	Hs
		734962 MP2K2_HUMAN (1-391): 2.96e-123: 363: 79.40		TRI67_HUMAN (1-783): 0: 593: 100.00
+	Hs
		625496 CDK2_HUMAN (65-367): 2.85e-123: 359: 24.27		TRI67_HUMAN (1-783): 0: 593: 100.00
+	Hs
		681909 AKT1_HUMAN (39-389): 1.97e-120: 359: 19.44		TRI67_HUMAN (1-783): 0: 593: 100.00
+	Hs
		682189 AKT2_HUMAN (20-377): 7.89e-112: 337: 20.71		TRI67_HUMAN (1-783): 0: 593: 100.00
+	Hs
		1023065 STK4_HUMAN (37-369): 2.53e-111: 336: 30.06		TRI67_HUMAN (1-783): 0: 593: 100.00
+	Hs
		1027387 STK3_HUMAN (50-369): 2.6e-109: 331: 33.23		TRI67_HUMAN (1-783): 0: 593: 100.00
+	Hs
		414967 CDK1_HUMAN (65-367): 7.64e-110: 325: 26.45		TRI67_HUMAN (1-783): 0: 593: 100.00
+	Hs
		1172483 STK24_HUMAN (65-364): 1.58e-102: 312: 32.12		TRI67_HUMAN (1-783): 0: 593: 100.00
+	Hs
		805440 MP2K3_HUMAN (53-380): 1.39e-65: 214: 36.69		TRI67_HUMAN (1-783): 0: 593: 100.00
+	Hs
		153141 MP2K7_HUMAN (35-375): 7.04e-61: 204: 35.49		TRI67_HUMAN (1-783): 0: 593: 100.00
+	Hs
		800987 MP2K4_HUMAN (66-388): 2.41e-60: 202: 36.20		TRI67_HUMAN (1-783): 0: 593: 100.00
+	Hs
		960115 CDK3_HUMAN (65-379): 5.96e-120: 351: 21.81		TRI63_HUMAN (298-505): 1.17e-83: 272: 27.40
+	Hs
		960118 CDK3_HUMAN (65-379): 5.96e-120: 351: 21.81		TRI55_HUMAN (189-505): 9.32e-81: 270: 19.57
+	Hs
		584875 CDK2_HUMAN (65-367): 2.85e-123: 359: 24.27		RO52_HUMAN (120-378): 1.33e-12: 72.8: 10.81
+	Hs
		414916 CDK1_HUMAN (65-367): 7.64e-110: 325: 26.45		TRI25_HUMAN (1-158): 8.85e-09: 60.9: 13.29
+	Hs
		131546 STK25_HUMAN (50-367): 4.36e-103: 312: 31.88		TRI27_HUMAN (105-456): 1.65e-10: 66.3: 14.77
+	Hs
		537109 STK26_HUMAN (65-367): 5.81e-103: 312: 31.80		TRI27_HUMAN (105-456): 1.65e-10: 66.3: 14.77