Interactor 1: EPHA4 (Q03137)
Ephrin type-A receptor 4 (EC 2.7.10.1) (Tyrosine-protein kinase receptor MPK-3) (Tyrosine-protein kinase receptor SEK-1)
Gene: EPHA4
Interactor 2: NGEF (Q8CHT1)
Ephexin-1 (Eph-interacting exchange protein) (Neuronal guanine nucleotide exchange factor)
Gene: NGEF
Species: Mus musculus
Source: intact
Category: Small-scale
Confidence: High
| Method score | Annotation score | Interaction score |
|---|---|---|
| 0.38 | 1.00 | 0.618 |
The method score is based on:
| Property | Details |
|---|---|
| Experiments | 21029865 |
| Identification Methods | anti tag coimmunoprecipitation |
| Interaction Type | physical association |
The annotation score is based on:
| Property | Details |
|---|---|
| Interacting Pfam domains | RhoGEF~fn3, PH~PK_Tyr_Ser-Thr, PK_Tyr_Ser-Thr~SH3_1 |
| Common GO terms | GO:0043087 - regulation of GTPase activity GO:0046875 - ephrin receptor binding GO:0048013 - ephrin receptor signaling pathway GO:0098978 - glutamatergic synapse GO:1905806 - regulation of synapse pruning |
| Homologous interactions | 20 |
Homologous interactions (Top 20)
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Service provided by Combinatics, Japan
Last updated: 15 Jul 2024
