Protein: NEP1
Ribosomal RNA small subunit methyltransferase NEP1 (EC 2.1.1.-) (18S rRNA (pseudouridine(1248)-N1)-methyltransferase) (18S rRNA Psi1248 methyltransferase) (Nucleolar protein EMG1 homolog) (Protein C2f) (Ribosome biogenesis protein NEP1)

Gene: NEP1, EMG1
Organism: Homo sapiens
Interactions: 99
UniProt ID: Q92979

Gene Ontology (top 5):
GO:0001824 - blastocyst development
GO:0003723 - RNA binding
GO:0005634 - nucleus
GO:0005654 - nucleoplasm
GO:0005694 - chromosome

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

1273306

NEP1
Ribosomal RNA small subunit methyltransferase NEP1

2

1

High-throughput

0.783

High

940726

NOP14
Nucleolar protein 14

2

1

High-throughput

0.611

High

1240903

SERB1
SERPINE1 mRNA-binding protein 1

2

1

High-throughput

0.611

High

1085868

IF16
Gamma-interferon-inducible protein 16

2

0

High-throughput

0.585

High

1273321

ANLN
Anillin

2

0

High-throughput

0.585

High

1273317

ZN768
Zinc finger protein 768

2

0

High-throughput

0.580

High

166756

CE290
Centrosomal protein of 290 kDa

2

1

High-throughput

0.571

High

370150

ESR1
Estrogen receptor

2

1

High-throughput

0.571

High

210183

PRC1
Protein regulator of cytokinesis 1

2

0

High-throughput

0.561

High

553354

RFA2
Replication protein A 32 kDa subunit

2

0

High-throughput

0.559

High

651869

RFA1
Replication protein A 70 kDa DNA-binding subunit

2

0

High-throughput

0.559

High

721081

RFA3
Replication protein A 14 kDa subunit

2

0

High-throughput

0.559

High

935076

H31
Histone H3.1

2

0

High-throughput

0.559

High

1273315

3BHS7
3 beta-hydroxysteroid dehydrogenase type 7

2

1

High-throughput

0.553

High

127334

IPO5
Importin-5

1

1

High-throughput

0.536

High

1256963

IPO4
Importin-4

1

1

High-throughput

0.536

High

1273312

NOC4L
Nucleolar complex protein 4 homolog

1

1

High-throughput

0.536

High

1273316

ZN106
Zinc finger protein 106

1

1

High-throughput

0.536

High

529513

CFTR
Cystic fibrosis transmembrane conductance regulator

1

0

High-throughput

0.518

High

991837

KHDR1
KH domain-containing, RNA-binding, signal transduction-associated protein 1

1

0

High-throughput

0.518

High

418517

NPM
Nucleophosmin

1

0

High-throughput

0.513

High

551230

ITF2
Transcription factor 4

1

0

High-throughput

0.513

High

649650

RL10
Large ribosomal subunit protein uL16

1

0

High-throughput

0.513

High

728946

AHR
Aryl hydrocarbon receptor

1

0

High-throughput

0.513

High

1062607

EMC2
ER membrane protein complex subunit 2

1

0

High-throughput

0.513

High

1145657

ICE2
Little elongation complex subunit 2

1

0

High-throughput

0.513

High

455729

PARP1
Poly [ADP-ribose] polymerase 1

1

0

High-throughput

0.493

High

395386

A4
Amyloid-beta precursor protein

1

0

High-throughput

0.480

High

902705

SUMO2
Small ubiquitin-related modifier 2

1

0

High-throughput

0.480

High

244746

BRD4
Bromodomain-containing protein 4

1

1

High-throughput

0.479

High

268210

EED
Polycomb protein EED

1

1

High-throughput

0.479

High

322961

STAU1
Double-stranded RNA-binding protein Staufen homolog 1

1

1

High-throughput

0.479

High

944885

RED1
Double-stranded RNA-specific editase 1

1

1

High-throughput

0.479

High

1064008

TNIP1
TNFAIP3-interacting protein 1

1

1

High-throughput

0.479

High

1067083

BRD3
Bromodomain-containing protein 3

1

1

High-throughput

0.479

High

1128514

HABP4
Intracellular hyaluronan-binding protein 4

1

1

High-throughput

0.479

High

1269289

ESR2
Estrogen receptor beta

1

1

High-throughput

0.479

High

1273320

SMUF1
E3 ubiquitin-protein ligase SMURF1

1

2

High-throughput

0.479

High

1273323

AATF
Protein AATF

1

1

High-throughput

0.479

High

1273325

HECW2
E3 ubiquitin-protein ligase HECW2

1

2

High-throughput

0.479

High

1234167

ZCHC9
Zinc finger CCHC domain-containing protein 9

1

0

High-throughput

0.460

High

1241243

FA98A
Protein FAM98A

1

0

High-throughput

0.460

High

1243262

MCPH1
Microcephalin

1

0

Small-scale

0.460

High

205788

TGON2
Trans-Golgi network integral membrane protein 2

1

0

High-throughput

0.458

High

233570

NUPR1
Nuclear protein 1

1

0

High-throughput

0.458

High

255971

OBSL1
Obscurin-like protein 1

1

0

High-throughput

0.458

High

308950

KI20A
Kinesin-like protein KIF20A

1

0

High-throughput

0.458

High

347508

MYC
Myc proto-oncogene protein

1

0

High-throughput

0.458

High

615810

GCSP
Glycine dehydrogenase

1

0

High-throughput

0.458

High

717483

IL13
Interleukin-13

1

0

Small-scale

0.458

High

719041

PHB1
Prohibitin 1

1

0

High-throughput

0.458

High

818326

SOX2
Transcription factor SOX-2

1

0

High-throughput

0.458

High

964386

RUNX1
Runt-related transcription factor 1

1

0

High-throughput

0.458

High

967932

PO5F1
POU domain, class 5, transcription factor 1

1

0

High-throughput

0.458

High

1022166

NFX1
Transcriptional repressor NF-X1

1

0

High-throughput

0.458

High

1037142

MTX1
Metaxin-1

1

0

High-throughput

0.458

High

1064560

U5S1
116 kDa U5 small nuclear ribonucleoprotein component

1

0

High-throughput

0.458

High

1080202

EZH2
Histone-lysine N-methyltransferase EZH2

1

0

High-throughput

0.458

High

1081350

E2F4
Transcription factor E2F4

1

0

High-throughput

0.458

High

1159218

PRP8
Pre-mRNA-processing-splicing factor 8

1

0

High-throughput

0.458

High

1171094

TRI67
Tripartite motif-containing protein 67

1

0

High-throughput

0.458

High

1201579

ZCH18
Zinc finger CCCH domain-containing protein 18

1

0

High-throughput

0.458

High

1264155

DNJC9
DnaJ homolog subfamily C member 9

1

0

High-throughput

0.458

High

1272511

CSN5
COP9 signalosome complex subunit 5

1

0

High-throughput

0.458

High

1273308

DCPS
m7GpppX diphosphatase

1

0

High-throughput

0.458

High

1273310

RANB9
Ran-binding protein 9

1

0

High-throughput

0.458

High

1273314

DDA1
DET1- and DDB1-associated protein 1

1

0

High-throughput

0.458

High

1273318

ECT2
Protein ECT2

1

0

High-throughput

0.458

High

1273319

NANOG
Homeobox protein NANOG

1

0

High-throughput

0.458

High

1273322

SLX9
Ribosome biogenesis protein SLX9 homolog

1

0

Small-scale

0.458

High

1273324

UBP36
Ubiquitin carboxyl-terminal hydrolase 36

1

0

High-throughput

0.458

High

1273326

ZRAN1
Ubiquitin thioesterase ZRANB1

1

0

High-throughput

0.458

High

1273327

TBK1
Serine/threonine-protein kinase TBK1

1

0

High-throughput

0.458

High

1273329

FBW1A
F-box/WD repeat-containing protein 1A

1

0

High-throughput

0.458

High

1273330

TRRAP
Transformation/transcription domain-associated protein

1

0

High-throughput

0.458

High

519694

ANXA3
Annexin A3

1

0

High-throughput

0.438

High

550418

ZEP1
Zinc finger protein 40

1

0

High-throughput

0.438

High

986830

PSME1
Proteasome activator complex subunit 1

1

0

High-throughput

0.438

High

1120279

CEP55
Centrosomal protein of 55 kDa

1

0

High-throughput

0.438

High

1273307

NAA80
N-alpha-acetyltransferase 80

1

0

High-throughput

0.438

High

1273311

PSB7
Proteasome subunit beta type-7

1

0

High-throughput

0.438

High

1146698

A16L1
Autophagy-related protein 16-1

1

1

High-throughput

0.437

High

402315

JUN
Transcription factor Jun

1

0

High-throughput

0.426

High

1079564

NEDD8
NEDD8

1

0

Small-scale

0.426

High

831551

CEBPA
CCAAT/enhancer-binding protein alpha

1

0

High-throughput

0.391

High

1273328

RHG26
Rho GTPase-activating protein 26

2

0

High-throughput

0.298

High

1273309

S2538
Mitochondrial glycine transporter

1

0

High-throughput

0.282

High

363251

FINC
Fibronectin

1

0

High-throughput

0.279

Low

388895

CP1A1
Cytochrome P450 1A1

1

0

High-throughput

0.279

Low

1087781

RTN1
Reticulon-1

1

0

High-throughput

0.279

Low

1185465

LIGO2
Leucine-rich repeat and immunoglobulin-like domain-containing nogo receptor-interacting protein 2

1

0

High-throughput

0.279

Low

1190974

GOGA7
Golgin subfamily A member 7

1

0

High-throughput

0.279

Low

1192006

MILR1
Allergin-1

1

0

High-throughput

0.279

Low

1273331

WIF1
Wnt inhibitory factor 1

1

0

High-throughput

0.279

Low

1273313

TIM21
Mitochondrial import inner membrane translocase subunit Tim21

1

0

High-throughput

0.269

Low

1137121

FAM74
Protein FAM74A4/A6

1

0

High-throughput

0.268

Low

149143

CTRO
Citron Rho-interacting kinase

1

0

High-throughput

0.249

Low

534579

CATE
Cathepsin E

1

0

High-throughput

0.238

Low


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Last updated: 15 Jul 2024