Protein: RHG31
Rho GTPase-activating protein 31 (Cdc42 GTPase-activating protein)

Gene: RHG31, ARHGAP31
Organism: Homo sapiens
Interactions: 47
UniProt ID: Q2M1Z3

Gene Ontology (top 5):
GO:0005096 - GTPase activator activity
GO:0005829 - cytosol
GO:0005925 - focal adhesion
GO:0007264 - small GTPase-mediated signal transduction
GO:0017124 - SH3 domain binding

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

988407

RAC1
Ras-related C3 botulinum toxin substrate 1

3

20

High-throughput

0.854

High

375564

RASK
GTPase KRas

2

20

High-throughput

0.754

High

1154092

ITSN1
Intersectin-1

1

14

Small-scale

0.665

High

955234

CDC42
Cell division control protein 42 homolog

1

20

High-throughput

0.647

High

962107

RHOA
Transforming protein RhoA

1

20

High-throughput

0.647

High

1178693

TLN1
Talin-1

3

16

High-throughput

0.641

High

402775

CYTB
Cystatin-B

2

1

High-throughput

0.571

High

408076

TBB4A
Tubulin beta-4A chain

2

2

High-throughput

0.571

High

612237

ARF4
ADP-ribosylation factor 4

2

10

High-throughput

0.571

High

716564

PRDX3
Thioredoxin-dependent peroxide reductase, mitochondrial

2

5

High-throughput

0.571

High

732327

PRDX2
Peroxiredoxin-2

2

5

High-throughput

0.571

High

827196

ARL1
ADP-ribosylation factor-like protein 1

2

11

High-throughput

0.571

High

1014900

ARF1
ADP-ribosylation factor 1

2

10

High-throughput

0.571

High

1178691

LIMD1
LIM domain-containing protein 1

2

16

High-throughput

0.571

High

214298

MSI1H
RNA-binding protein Musashi homolog 1

2

4

High-throughput

0.521

High

551069

PCNA
Proliferating cell nuclear antigen

2

2

High-throughput

0.521

High

719440

PPIF
Peptidyl-prolyl cis-trans isomerase F, mitochondrial

2

6

High-throughput

0.521

High

1178679

DRS7B
Dehydrogenase/reductase SDR family member 7B

2

1

High-throughput

0.521

High

1178681

RM10
Large ribosomal subunit protein uL10m

2

1

High-throughput

0.521

High

1178688

GHC1
Mitochondrial glutamate carrier 1

2

4

High-throughput

0.521

High

172870

XPO1
Exportin-1

1

17

High-throughput

0.479

High

174249

ARHGA
Rho guanine nucleotide exchange factor 10

1

12

High-throughput

0.479

High

323402

TRI37
E3 ubiquitin-protein ligase TRIM37

1

18

High-throughput

0.479

High

648172

NDKB
Nucleoside diphosphate kinase B

1

4

High-throughput

0.479

High

660082

COF1
Cofilin-1

1

2

High-throughput

0.479

High

845666

MUC18
Cell surface glycoprotein MUC18

1

7

High-throughput

0.479

High

973934

RUXF
Small nuclear ribonucleoprotein F

1

6

High-throughput

0.479

High

994242

PP2AA
Serine/threonine-protein phosphatase 2A catalytic subunit alpha isoform

1

5

High-throughput

0.479

High

1156101

ZYX
Zyxin

1

8

High-throughput

0.479

High

1178682

NUP93
Nuclear pore complex protein Nup93

1

1

High-throughput

0.479

High

1178687

BOLA2
BolA-like protein 2

1

3

High-throughput

0.479

High

1178690

HACD3
Very-long-chain

1

2

High-throughput

0.479

High

716434

PRDX5
Peroxiredoxin-5, mitochondrial

1

0

High-throughput

0.458

High

1178689

CYLD
Ubiquitin carboxyl-terminal hydrolase CYLD

1

0

High-throughput

0.458

High

729879

1433B
14-3-3 protein beta/alpha

1

20

High-throughput

0.445

High

833632

NAA10
N-alpha-acetyltransferase 10

1

2

High-throughput

0.445

High

481297

HMGB1
High mobility group protein B1

1

11

High-throughput

0.437

High

1178678

RIF1
Telomere-associated protein RIF1

1

5

High-throughput

0.437

High

1178683

TM263
Transmembrane protein 263

1

1

High-throughput

0.437

High

1178692

RT17
Small ribosomal subunit protein uS17m

1

2

High-throughput

0.437

High

1178680

CR3L2
Cyclic AMP-responsive element-binding protein 3-like protein 2

1

6

High-throughput

0.407

High

168092

TIM23
Mitochondrial import inner membrane translocase subunit Tim23

2

0

High-throughput

0.298

High

784625

ATPG
ATP synthase F(1) complex subunit gamma, mitochondrial

2

0

High-throughput

0.298

High

1178685

SF3B5
Splicing factor 3B subunit 5

1

0

High-throughput

0.249

Low

1178686

NUCKS
Nuclear ubiquitous casein and cyclin-dependent kinase substrate 1

1

0

High-throughput

0.249

Low

1178694

CHCH2
Coiled-coil-helix-coiled-coil-helix domain-containing protein 2

1

0

High-throughput

0.249

Low

1178684

NEUL4
Neuralized-like protein 4

1

0

High-throughput

0.232

Low


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Last updated: 11Aug2025