HitPredict

Interactor 1: PTH1R (Q03431)
Parathyroid hormone/parathyroid hormone-related peptide receptor (PTH/PTHrP type I receptor) (PTH/PTHr receptor) (Parathyroid hormone 1 receptor) (PTH1 receptor)
Gene: PTH1R

Interactor 2: S12A9 (Q9BXP2)
Solute carrier family 12 member 9 (Cation-chloride cotransporter 6) (hCCC6) (Cation-chloride cotransporter-interacting protein 1) (CCC-interacting protein 1) (hCIP1) (Potassium-chloride transporter 9) (WO3.3)
Gene: SLC12A9

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.62	0.60	0.611

Property	Details
Experiments	26186194, 28514442
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005886 - plasma membrane
Homologous interactions	10

Homologous interactions

Color coding for hit scores

	1 593 Hs			1 914
+	Hs
		976381 PTH1R_HUMAN (1-593): 0: 618: 100.00		S12A4_HUMAN (1-912): 0: 725: 22.83
+	Hs
		976384 PTH1R_HUMAN (1-593): 0: 618: 100.00		S12A7_HUMAN (1-912): 0: 718: 22.94
+	Hs
		825077 PTH2R_HUMAN (22-582): 2.88e-135: 407: 46.38		CTR3_HUMAN (7-443): 9.26e-89: 297: 18.57
+	Hs
		686340 VIPR1_HUMAN (53-515): 1.17e-115: 353: 35.10		YLAT2_HUMAN (7-517): 1.01e-105: 339: 12.17
+	Hs
		676515 VIPR1_HUMAN (53-515): 1.17e-115: 353: 35.10		CTR1_HUMAN (13-443): 7.98e-97: 319: 16.59
+	Hs
		686273 VIPR1_HUMAN (53-515): 1.17e-115: 353: 35.10		CTR2_HUMAN (26-443): 1.01e-94: 314: 16.63
+	Hs
		783698 VIPR2_HUMAN (58-497): 3.87e-103: 320: 35.29		YLAT2_HUMAN (7-517): 1.01e-105: 339: 12.17
+	Hs
		225276 AGRB3_HUMAN (27-574): 3.44e-87: 297: 13.28		CTR1_HUMAN (13-443): 7.98e-97: 319: 16.59
+	Hs
		1224673 AGRG2_HUMAN (146-497): 5.09e-72: 251: 16.76		CTR3_HUMAN (7-443): 9.26e-89: 297: 18.57
+	Hs
		1252611 AGRE2_HUMAN (187-504): 1.58e-42: 165: 19.39		S7A14_HUMAN (34-443): 2.18e-65: 236: 16.83