Protein: SEC7
ADP-ribosylation factor guanine nucleotide-exchange factor SEC7 (ARF-GEP SEC7)

Gene: SEC7
Organism: Saccharomyces cerevisiae S288C
Interactions: 115
UniProt ID: P11075

Gene Ontology (top 5):
GO:0000045 - autophagosome assembly
GO:0005085 - guanyl-nucleotide exchange factor activity
GO:0005770 - late endosome
GO:0005798 - Golgi-associated vesicle
GO:0005802 - trans-Golgi network

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

535966

SEC7
ADP-ribosylation factor guanine nucleotide-exchange factor SEC7

4

9

Small-scale

0.883

High

535967

ARF1
ADP-ribosylation factor 1

2

15

Small-scale

0.754

High

536028

RSP5
E3 ubiquitin-protein ligase RSP5

3

1

Small-scale

0.677

High

536012

ARL1
ADP-ribosylation factor-like protein 1

1

20

Small-scale

0.647

High

525744

HSP72
Heat shock protein SSA2

3

5

High-throughput

0.624

High

535999

CSE1
Importin alpha re-exporter

2

2

High-throughput

0.621

High

536015

YPT31
GTP-binding protein YPT31/YPT8

2

7

Small-scale

0.602

High

535968

SSB1
Ribosome-associated molecular chaperone SSB1

2

5

High-throughput

0.601

High

531217

METK1
S-adenosylmethionine synthase 1

2

0

High-throughput

0.595

High

536021

PIK1
Phosphatidylinositol 4-kinase PIK1

1

3

Small-scale

0.573

High

522853

HSP71
Heat shock protein SSA1

2

5

High-throughput

0.571

High

535979

SIS1
Protein SIS1

2

1

High-throughput

0.571

High

536044

APJ1
J domain-containing protein APJ1

2

3

High-throughput

0.571

High

535978

MPCP
Mitochondrial phosphate carrier protein

2

1

High-throughput

0.567

High

536019

YHI0
Putative proline--tRNA ligase YHR020W

2

1

High-throughput

0.567

High

536023

DHH1
ATP-dependent RNA helicase DHH1

2

2

High-throughput

0.567

High

536035

GCN20
Protein GCN20

2

1

High-throughput

0.567

High

536000

PLSC
1-acyl-sn-glycerol-3-phosphate acyltransferase

2

1

High-throughput

0.537

High

536029

IMB4
Importin subunit beta-4

2

2

High-throughput

0.537

High

535976

CSK22
Casein kinase II subunit alpha'

1

4

High-throughput

0.536

High

535985

PEP3
Vacuolar membrane protein PEP3

1

2

High-throughput

0.536

High

536027

RV167
Reduced viability upon starvation protein 167

1

4

High-throughput

0.536

High

535973

SEC23
Protein transport protein SEC23

2

1

Small-scale

0.521

High

484258

KEX1
Pheromone-processing carboxypeptidase KEX1

1

0

High-throughput

0.518

High

535969

KEX2
Kexin

1

0

High-throughput

0.518

High

536059

CHS5
Chitin biosynthesis protein CHS5

1

0

High-throughput

0.518

High

448619

SNF1
Carbon catabolite-derepressing protein kinase

1

0

High-throughput

0.513

High

531572

RL4A
Large ribosomal subunit protein uL4A

1

0

High-throughput

0.513

High

536006

ALY1
Arrestin-related trafficking adapter 6

1

0

High-throughput

0.513

High

376261

YPT1
GTP-binding protein YPT1

1

9

Small-scale

0.501

High

536042

YPT32
GTP-binding protein YPT32/YPT11

1

7

Small-scale

0.501

High

535996

ATC5
Phospholipid-transporting ATPase DNF1

1

2

High-throughput

0.494

High

485989

TBA1
Tubulin alpha-1 chain

1

1

High-throughput

0.489

High

535980

SSK22
Serine/threonine-protein kinase SSK22

1

1

High-throughput

0.489

High

535998

UBC6
Ubiquitin-conjugating enzyme E2 6

1

1

High-throughput

0.489

High

536034

MPG1
Mannose-1-phosphate guanyltransferase

1

1

High-throughput

0.489

High

535982

SRO9
RNA-binding protein SRO9

1

2

High-throughput

0.479

High

535983

CDC48
Cell division control protein 48

1

5

High-throughput

0.479

High

535989

HS104
Heat shock protein 104

1

2

High-throughput

0.479

High

535990

COPG
Coatomer subunit gamma

1

8

Small-scale

0.479

High

536004

RS27A
Small ribosomal subunit protein eS27A

1

1

High-throughput

0.479

High

536026

LAA1
AP-1 accessory protein LAA1

1

1

High-throughput

0.479

High

536050

SCC2
Sister chromatid cohesion protein 2

1

2

High-throughput

0.479

High

536060

RIO1
Serine/threonine-protein kinase RIO1

1

1

High-throughput

0.479

High

383467

RS17A
Small ribosomal subunit protein eS17A

1

0

High-throughput

0.458

High

434750

RS3
Small ribosomal subunit protein uS3

1

0

High-throughput

0.458

High

441655

RS14A
Small ribosomal subunit protein uS11A

1

0

High-throughput

0.458

High

502795

RS22A
Small ribosomal subunit protein uS8A

1

0

High-throughput

0.458

High

512768

RS8A
Small ribosomal subunit protein eS8A

1

0

High-throughput

0.458

High

514405

RS18A
Small ribosomal subunit protein uS13A

1

0

High-throughput

0.458

High

535981

RS2
Small ribosomal subunit protein uS5

1

0

High-throughput

0.458

High

535984

RS7A
Small ribosomal subunit protein eS7A

1

0

High-throughput

0.458

High

536040

RS12
Small ribosomal subunit protein eS12

1

0

High-throughput

0.458

High

536057

RS10A
Small ribosomal subunit protein eS10A

1

0

High-throughput

0.458

High

536025

ATC3
Phospholipid-transporting ATPase DRS2

1

2

High-throughput

0.457

High

394153

EF1A
Elongation factor 1-alpha

1

1

High-throughput

0.445

High

535994

HSP7F
Heat shock protein homolog SSE1

1

8

High-throughput

0.445

High

535995

HSP79
Heat shock protein homolog SSE2

1

8

High-throughput

0.445

High

536003

YET1
Endoplasmic reticulum transmembrane protein 1

1

1

High-throughput

0.445

High

536018

APM2
Adaptin medium chain homolog APM2

1

2

High-throughput

0.445

High

536020

SSZ1
Ribosome-associated complex subunit SSZ1

1

4

High-throughput

0.445

High

536030

SSB2
Ribosome-associated molecular chaperone SSB2

1

5

High-throughput

0.445

High

536033

COPB
Coatomer subunit beta

1

4

Small-scale

0.445

High

536049

HMO1
High mobility group protein 1

1

1

High-throughput

0.445

High

536051

SNX41
Sorting nexin-41

1

2

High-throughput

0.445

High

536054

VIP1
Inositol hexakisphosphate and diphosphoinositol-pentakisphosphate kinase

1

1

High-throughput

0.445

High

535988

TF2B
Transcription initiation factor IIB

1

2

High-throughput

0.437

High

536008

LONM
Lon protease homolog, mitochondrial

1

7

High-throughput

0.437

High

536010

ANM1
Protein arginine N-methyltransferase 1

1

6

High-throughput

0.437

High

536031

SEC24
Protein transport protein SEC24

1

1

Small-scale

0.437

High

536041

HFM1
ATP-dependent DNA helicase MER3

1

1

Small-scale

0.437

High

536047

TOM1
E3 ubiquitin-protein ligase TOM1

1

1

High-throughput

0.437

High

536048

RUVB1
RuvB-like protein 1

1

2

High-throughput

0.437

High

536061

RUVB2
RuvB-like protein 2

1

2

High-throughput

0.437

High

536002

RS3A1
Small ribosomal subunit protein eS1A

1

0

High-throughput

0.426

High

536045

UBC7
Ubiquitin-conjugating enzyme E2 7

1

1

High-throughput

0.417

High

535972

SEC63
Protein translocation protein SEC63

1

6

High-throughput

0.407

High

535977

ZRC1
Vacuolar zinc transporter ZRC1

1

7

High-throughput

0.407

High

535987

LAC1
Ceramide synthase LAC1

1

2

High-throughput

0.407

High

535991

SAC1
Phosphatidylinositol-3-phosphatase SAC1

1

1

High-throughput

0.407

High

536001

HSP78
Heat shock protein 78, mitochondrial

1

2

High-throughput

0.407

High

536007

GPT2
Glycerol-3-phosphate O-acyltransferase 2

1

1

High-throughput

0.407

High

536009

CDC27
Anaphase-promoting complex subunit CDC27

1

1

High-throughput

0.407

High

536014

MKAR
Very-long-chain 3-oxoacyl-CoA reductase

1

2

High-throughput

0.407

High

536062

NOP58
Nucleolar protein 58

1

1

High-throughput

0.407

High

535971

GFA1
Glutamine--fructose-6-phosphate aminotransferase [isomerizing]

2

0

High-throughput

0.324

High

535986

IDH2
Isocitrate dehydrogenase [NAD] subunit 2, mitochondrial

2

0

High-throughput

0.324

High

536013

KTR3
Probable mannosyltransferase KTR3

2

0

High-throughput

0.324

High

536016

FKS1
1,3-beta-glucan synthase component FKS1

2

0

High-throughput

0.324

High

536036

DUG1
Cys-Gly metallodipeptidase DUG1

2

0

High-throughput

0.324

High

358096

ADH1
Alcohol dehydrogenase 1

2

0

High-throughput

0.307

High

536011

MAK5
ATP-dependent RNA helicase MAK5

2

0

High-throughput

0.307

High

535993

SMI1
Cell wall assembly regulator SMI1

1

0

High-throughput

0.282

High

427103

RLA0
Large ribosomal subunit protein uL10

1

0

High-throughput

0.279

Low

535970

RED1
Protein RED1

1

0

High-throughput

0.279

Low

536038

GWT1
GPI-anchored wall transfer protein 1

1

0

High-throughput

0.279

Low

536017

PPX1
Polyphosphatase

1

0

High-throughput

0.269

Low

535992

PRP21
Pre-mRNA-splicing factor PRP21

1

0

High-throughput

0.265

Low

535975

RPB3
DNA-directed RNA polymerase II subunit RPB3

1

0

High-throughput

0.249

Low

536005

CENPA
Histone H3-like centromeric protein CSE4

1

0

High-throughput

0.249

Low

536022

YCFI
Metal resistance protein YCF1

1

0

High-throughput

0.249

Low

536043

PESC
Pescadillo homolog

1

0

High-throughput

0.249

Low

536046

ESP1
Separin

1

0

High-throughput

0.249

Low

536053

MMS22
E3 ubiquitin-protein ligase substrate receptor MMS22

1

0

High-throughput

0.249

Low

536055

SGO1
Shugoshin

1

0

High-throughput

0.249

Low

536056

ESA1
Histone acetyltransferase ESA1

1

0

Small-scale

0.249

Low

536058

PIN2
[PSI+] induction protein 2

1

0

High-throughput

0.238

Low

535974

VATB
V-type proton ATPase subunit B

1

0

High-throughput

0.232

Low

535997

PMP1
Plasma membrane ATPase proteolipid 1

1

0

High-throughput

0.232

Low

536024

YM11
Uncharacterized protein YMR124W

1

0

High-throughput

0.232

Low

536032

SNL1
HSP70 co-chaperone SNL1

1

0

High-throughput

0.232

Low

536037

RPA34
DNA-directed RNA polymerase I subunit RPA34

1

0

High-throughput

0.232

Low

536039

PFD3
Prefoldin subunit 3

1

0

High-throughput

0.232

Low

536052

HSP31
Glutathione-independent glyoxalase HSP31

1

0

High-throughput

0.232

Low


Service provided by Combinatics, Japan

Last updated: 11Aug2025