HitPredict

Interactor 1: NHP10 (Q03435)
Non-histone protein 10 (High mobility group protein 2)
Gene: NHP10

Interactor 2: ARP8 (Q12386)
Actin-like protein ARP8
Gene: ARP8

Species: Saccharomyces cerevisiae S288C

Source: mint

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.88	0.60	0.730

Property	Details
Experiments	11805826, 30120252, 15607974, 16554755, 16429126, 37968396
Identification Methods	tandem affinity purification, affinity chromatography technology
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005634 - nucleus GO:0006281 - DNA repair GO:0006302 - double-strand break repair GO:0006338 - chromatin remodeling GO:0006355 - regulation of DNA-templated transcription and 1 others more... GO:0031011 - Ino80 complex
Homologous interactions	8

Homologous interactions

Color coding for hit scores

	1 203 Sc			1 881
+	Sc
		514223 NHP6A_YEAST (78-162): 3.8e-25: 95.6: 31.46		ARP8_YEAST (1-881): 0: 789: 100.00
+	Sc
		887661 NHP10_YEAST (1-203): 5.56e-62: 193: 100.00		ACT_YEAST (730-877): 3.32e-52: 188: 15.66
+	Hs
		932341 CIC_HUMAN (44-201): 6.64e-29: 114: 16.76		ACTC_HUMAN (706-877): 1.36e-54: 195: 14.15
+	Hs
		175761 HMGB3_HUMAN (90-160): 1.02e-23: 94.9: 32.00		ACTB_HUMAN (730-877): 6.7e-56: 199: 15.66
+	Sc
		514201 NHP6A_YEAST (78-162): 3.8e-25: 95.6: 31.46		ACT_YEAST (730-877): 3.32e-52: 188: 15.66
+	Hs
		449663 HMGB1_HUMAN (80-160): 1.31e-19: 84.5: 31.77		ACTC_HUMAN (706-877): 1.36e-54: 195: 14.15
+	Hs
		449751 HMGB1_HUMAN (80-160): 1.31e-19: 84.5: 31.77		POTEE_HUMAN (93-265): 1.35e-42: 170: 16.58
+	Hs
		818119 SOX2_HUMAN (63-178): 1.49e-29: 112: 15.00		ACTBL_HUMAN (404-643): 2.3e-14: 77.9: 17.86