HitPredict

Interactor 1: ACTA (P62736)
Actin, aortic smooth muscle (EC 3.6.4.-) (Alpha-actin-2) (Cell growth-inhibiting gene 46 protein) [Cleaved into: Actin, aortic smooth muscle, intermediate form]
Gene: ACTA2

Interactor 2: CALD1 (Q05682)
Caldesmon (CDM)
Gene: CALD1

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.479

Property	Details
Experiments	37071682
Identification Methods	cross-linking study
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0001725 - stress fiber GO:0005829 - cytosol GO:0015629 - actin cytoskeleton
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 377 Hs			1 793
+	Hs
		1052034 ACTBL_HUMAN (4-377): 0: 712: 87.97		CALD1_HUMAN (1-793): 4.89e-41: 163: 100.00
+	Hs
		1143145 ACTBL_HUMAN (4-377): 0: 712: 87.97		PLEC_HUMAN (12-768): 3.36e-22: 105: 12.58
+	Hs
		1154094 ACTBL_HUMAN (4-377): 0: 712: 87.97		ITSN1_HUMAN (5-350): 3.71e-22: 104: 17.43
+	Hs
		772838 ACTBL_HUMAN (4-377): 0: 712: 87.97		MYH9_HUMAN (10-659): 9.61e-22: 103: 9.76
+	Hs
		995552 ACTC_HUMAN (1-377): 0: 595: 98.41		CALD1_HUMAN (1-793): 4.89e-41: 163: 100.00
+	Hs
		993144 ACTG_HUMAN (4-377): 0: 594: 94.39		CALD1_HUMAN (1-793): 4.89e-41: 163: 100.00
+	Hs
		995735 ACTC_HUMAN (1-377): 0: 595: 98.41		MY18A_HUMAN (9-628): 1.86e-28: 125: 15.98
+	Hs
		996511 ACTS_HUMAN (1-377): 0: 595: 97.88		MY18A_HUMAN (9-628): 1.86e-28: 125: 15.98
+	Hs
		993275 ACTG_HUMAN (4-377): 0: 594: 94.39		MY18A_HUMAN (9-628): 1.86e-28: 125: 15.98
+	Hs
		995607 ACTC_HUMAN (1-377): 0: 595: 98.41		PLEC_HUMAN (12-768): 3.36e-22: 105: 12.58
+	Hs
		996459 ACTS_HUMAN (1-377): 0: 595: 97.88		PLEC_HUMAN (12-768): 3.36e-22: 105: 12.58
+	Hs
		773154 ACTC_HUMAN (1-377): 0: 595: 98.41		MYH10_HUMAN (1-631): 5.25e-22: 104: 9.40
+	Hs
		993183 ACTG_HUMAN (4-377): 0: 594: 94.39		PLEC_HUMAN (12-768): 3.36e-22: 105: 12.58
+	Hs
		996460 ACTS_HUMAN (1-377): 0: 595: 97.88		ITSN1_HUMAN (5-350): 3.71e-22: 104: 17.43
+	Hs
		772733 ACTC_HUMAN (1-377): 0: 595: 98.41		MYH9_HUMAN (10-659): 9.61e-22: 103: 9.76
+	Hs
		772734 ACTS_HUMAN (1-377): 0: 595: 97.88		MYH9_HUMAN (10-659): 9.61e-22: 103: 9.76
+	Hs
		993189 ACTG_HUMAN (4-377): 0: 594: 94.39		ITSN1_HUMAN (5-350): 3.71e-22: 104: 17.43
+	Hs
		772729 ACTG_HUMAN (4-377): 0: 594: 94.39		MYH9_HUMAN (10-659): 9.61e-22: 103: 9.76
+	Hs
		157222 ACTC_HUMAN (1-377): 0: 595: 98.41		CTRO_HUMAN (122-718): 9.4e-15: 81: 9.87
+	Hs
		995837 ACTC_HUMAN (1-377): 0: 595: 98.41		MYO5C_HUMAN (13-485): 5.43e-09: 62.2: 14.38