HitPredict

Interactor 1: RHOB (P62745)
Rho-related GTP-binding protein RhoB (Rho cDNA clone 6) (h6)
Gene: RHOB

Interactor 2: LIPA1 (Q13136)
Liprin-alpha-1 (LAR-interacting protein 1) (LIP-1) (Protein tyrosine phosphatase receptor type f polypeptide-interacting protein alpha-1) (PTPRF-interacting protein alpha-1)
Gene: PPFIA1

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.56	0.60	0.584

Property	Details
Experiments	34079125, 31871319
Identification Methods	proximity labelling technology, affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005829 - cytosol GO:0005925 - focal adhesion GO:0007165 - signal transduction GO:0098685 - Schaffer collateral - CA1 synapse
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 196 Hs			1 1202
+	Hs
		988329 RAC1_HUMAN (1-196): 1.47e-79: 236: 55.10		LIPA1_HUMAN (1-1202): 1.11e-166: 528: 100.00
+	Hs
		962005 RHOA_HUMAN (1-196): 4.38e-78: 233: 83.67		LIPA1_HUMAN (1-1202): 1.11e-166: 528: 100.00
+	Hs
		581017 RAC2_HUMAN (1-196): 4.54e-77: 230: 53.57		LIPA1_HUMAN (1-1202): 1.11e-166: 528: 100.00
+	Hs
		1015404 RHOG_HUMAN (1-196): 3.36e-76: 228: 51.53		LIPA1_HUMAN (1-1202): 1.11e-166: 528: 100.00
+	Hs
		466231 RHOC_HUMAN (1-196): 8.71e-76: 227: 83.16		LIPA1_HUMAN (1-1202): 1.11e-166: 528: 100.00
+	Hs
		955113 CDC42_HUMAN (1-196): 7.26e-75: 225: 49.49		LIPA1_HUMAN (1-1202): 1.11e-166: 528: 100.00
+	Hs
		988578 RAC1_HUMAN (1-196): 1.47e-79: 236: 55.10		MY18A_HUMAN (176-843): 2.33e-24: 113: 10.42
+	Hs
		962335 RHOA_HUMAN (1-196): 4.38e-78: 233: 83.67		MY18A_HUMAN (176-843): 2.33e-24: 113: 10.42
+	Hs
		978205 RHOB_HUMAN (1-196): 8.92e-78: 232: 100.00		MY18A_HUMAN (176-843): 2.33e-24: 113: 10.42
+	Hs
		581208 RAC2_HUMAN (1-196): 4.54e-77: 230: 53.57		MY18A_HUMAN (176-843): 2.33e-24: 113: 10.42
+	Hs
		773156 RHOG_HUMAN (1-196): 3.36e-76: 228: 51.53		MYH10_HUMAN (44-609): 2.55e-18: 93.5: 15.52
+	Hs
		773143 CDC42_HUMAN (1-196): 7.26e-75: 225: 49.49		MYH10_HUMAN (44-609): 2.55e-18: 93.5: 15.52
+	Hs
		772724 RAC1_HUMAN (1-196): 1.47e-79: 236: 55.10		MYH9_HUMAN (300-869): 4.94e-13: 76.4: 11.41
+	Hs
		988496 RAC1_HUMAN (1-196): 1.47e-79: 236: 55.10		LIPB1_HUMAN (277-521): 3.39e-12: 73.2: 15.51
+	Hs
		962229 RHOA_HUMAN (1-196): 4.38e-78: 233: 83.67		LIPB1_HUMAN (277-521): 3.39e-12: 73.2: 15.51
+	Hs
		978128 RHOB_HUMAN (1-196): 8.92e-78: 232: 100.00		LIPB1_HUMAN (277-521): 3.39e-12: 73.2: 15.51
+	Hs
		772743 RHOG_HUMAN (1-196): 3.36e-76: 228: 51.53		MYH9_HUMAN (300-869): 4.94e-13: 76.4: 11.41
+	Hs
		581146 RAC2_HUMAN (1-196): 4.54e-77: 230: 53.57		LIPB1_HUMAN (277-521): 3.39e-12: 73.2: 15.51
+	Hs
		1015569 RHOG_HUMAN (1-196): 3.36e-76: 228: 51.53		LIPB1_HUMAN (277-521): 3.39e-12: 73.2: 15.51
+	Hs
		466337 RHOC_HUMAN (1-196): 8.71e-76: 227: 83.16		LIPB1_HUMAN (277-521): 3.39e-12: 73.2: 15.51