HitPredict

Interactor 1: SPC19 (Q03954)
DASH complex subunit SPC19 (19 kDa spindle pole component protein) (Outer kinetochore protein SPC19)
Gene: SPC19

Interactor 2: DAD1 (Q12248)
DASH complex subunit DAD1 (DUO1 and DAM1-interacting protein 1) (Outer kinetochore protein DAD1)
Gene: DAD1

Species: Saccharomyces cerevisiae S288C

Source: mint

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.92	0.55	0.712

The method score is based on:

Property	Details
Experiments	11756468, 17634282, 12408861, 11782438, 16554755, 15640796, 37968396
Identification Methods	tandem affinity purification, two hybrid, affinity chromatography technology, biochemical
Interaction Type	physical association, direct interaction, association

The annotation score is based on:

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005737 - cytoplasm GO:0005876 - spindle microtubule GO:0008608 - attachment of spindle microtubules to kinetochore GO:0031116 - positive regulation of microtubule polymerization GO:0042729 - DASH complex and 5 others more... GO:0051301 - cell division GO:0051987 - positive regulation of attachment of spindle microtubules to kinetochore GO:0072686 - mitotic spindle GO:1990758 - mitotic sister chromatid biorientation GO:1990976 - protein transport along microtubule to mitotic spindle pole body
Homologous interactions	0

Service provided by Combinatics, Japan

Last updated: 15 Jul 2024