Interactor 1: TF65 (Q04206)
Transcription factor p65 (Nuclear factor NF-kappa-B p65 subunit) (Nuclear factor of kappa light polypeptide gene enhancer in B-cells 3)
Gene: RELA

Interactor 2: SETD7 (Q8WTS6)
Histone-lysine N-methyltransferase SETD7 (EC 2.1.1.364) (Histone H3-K4 methyltransferase SETD7) (H3-K4-HMTase SETD7) (Lysine N-methyltransferase 7) (SET domain-containing protein 7) (SET7/9)
Gene: SETD7

Species: Homo sapiens

Source: mint

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.85 0.55 0.686

The method score is based on:

Property Details
Experiments 19262565, 19864627, 18650421, 21131967
Identification Methods enzymatic study, affinity chromatography technology, pull down, methyltransferase assay, anti tag coimmunoprecipitation, anti bait coimmunoprecipitation
Interaction Type direct interaction, physical association, methylation reaction

The annotation score is based on:

Property Details
Interacting Pfam domains -
Common GO terms GO:0003682 - chromatin binding
GO:0005634 - nucleus
GO:0005654 - nucleoplasm
GO:0006325 - chromatin organization
GO:0045893 - positive regulation of DNA-templated transcription
Homologous interactions 0

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Last updated: 15 Jul 2024