HitPredict

Interactor 1: RSE1 (Q04693)
Pre-mRNA-splicing factor RSE1 (RNA splicing and ER to Golgi transport factor 1) (Spliceosome-associated protein 130)
Gene: RSE1

Interactor 2: CWC2 (Q12046)
Pre-mRNA-splicing factor CWC2 (Complexed with CEF1 protein 2) (PRP19-associated complex protein 40) (Synthetic lethal with CLF1 protein 3)
Gene: CWC2

Species: Saccharomyces cerevisiae S288C

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.70	1.00	0.839

Property	Details
Experiments	16429126, 37968396, 14690591
Identification Methods	affinity chromatography technology, tandem affinity purification, pull down
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	CPSF_A~RRM_1
Common GO terms	GO:0000398 - mRNA splicing, via spliceosome
Homologous interactions	4

Homologous interactions

Color coding for hit scores

	1 1361 Sc			1 339
+	Sc
		960469 RSE1_YEAST (1-1361): 0: 1246: 100.00		NAM8_YEAST (6-233): 3.5e-25: 107: 15.16
+	Sp
		953386 RSE1_SCHPO (57-1359): 0: 894: 22.90		CWC2_SCHPO (7-302): 1.19e-76: 242: 35.64
+	Hs
		165487 SF3B3_HUMAN (58-1360): 0: 1037: 23.11		SR140_HUMAN (123-296): 1.8e-12: 70.3: 18.56
+	Hs
		165493 DDB1_HUMAN (59-1356): 0: 942: 14.85		SR140_HUMAN (123-296): 1.8e-12: 70.3: 18.56