HitPredict

Interactor 1: H2B1C (P62807)
Histone H2B type 1-C/E/F/G/I (Histone H2B.1 A) (Histone H2B.a) (H2B/a) (Histone H2B.g) (H2B/g) (Histone H2B.h) (H2B/h) (Histone H2B.k) (H2B/k) (Histone H2B.l) (H2B/l)
Gene: H2BC4

Interactor 2: CDK5 (Q00535)
Cyclin-dependent kinase 5 (EC 2.7.11.1) (Cell division protein kinase 5) (Cyclin-dependent-like kinase 5) (Serine/threonine-protein kinase PSSALRE) (Tau protein kinase II catalytic subunit) (TPKII catalytic subunit)
Gene: CDK5

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.479

Property	Details
Experiments	34349018
Identification Methods	cross-linking study
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005634 - nucleus GO:0005654 - nucleoplasm GO:0005829 - cytosol
Homologous interactions	7

Homologous interactions

Color coding for hit scores

	1 126 Hs			1 292
+	Hs
		667887 H2B2E_HUMAN (1-126): 5.64e-54: 166: 99.21		CDK2_HUMAN (1-292): 7.63e-142: 402: 59.39
+	Hs
		667578 H2B1B_HUMAN (1-126): 1.53e-53: 165: 97.62		CDK2_HUMAN (1-292): 7.63e-142: 402: 59.39
+	Hs
		256834 H2B1K_HUMAN (1-126): 1.31e-53: 166: 99.21		CDK5_HUMAN (1-292): 1.13e-137: 391: 100.00
+	Hs
		443222 H2B1B_HUMAN (1-126): 1.53e-53: 165: 97.62		CDK1_HUMAN (1-289): 2.07e-133: 381: 56.01
+	Hs
		897373 H2B1L_HUMAN (1-126): 2.19e-52: 163: 98.41		CDK7_HUMAN (2-292): 3.01e-127: 367: 45.24
+	Hs
		1025621 H2B2E_HUMAN (1-126): 5.64e-54: 166: 99.21		CDK17_HUMAN (1-291): 2.34e-121: 359: 55.82
+	Hs
		322105 H2B2E_HUMAN (1-126): 5.64e-54: 166: 99.21		CDK14_HUMAN (4-291): 1.18e-103: 311: 54.61