HitPredict

Interactor 1: TLE2 (Q04725)
Transducin-like enhancer protein 2 (Enhancer of split groucho-like protein 2) (ESG2)
Gene: TLE2

Interactor 2: BARH1 (Q9BZE3)
BarH-like 1 homeobox protein
Gene: BARHL1

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.48	0.60	0.541

Property	Details
Experiments	20211142
Identification Methods	two hybrid, two hybrid array
Interaction Type	direct interaction, physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005634 - nucleus
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 743 Hs			1 327
+	Hs
		724225 TLE2_HUMAN (1-743): 0: 552: 100.00		MSX2_HUMAN (96-296): 1.01e-34: 129: 30.88
+	Mm
		623700 TLE4_MOUSE (1-743): 1.35e-176: 526: 65.93		PAX3_MOUSE (31-325): 1.53e-37: 141: 19.08
+	Hs
		620144 TLE4_HUMAN (1-743): 3.3e-176: 525: 65.93		PAX7_HUMAN (31-325): 9.12e-36: 137: 18.15
+	Hs
		641379 TLE4_HUMAN (1-743): 3.3e-176: 525: 65.93		PAX6_HUMAN (31-325): 3.83e-36: 136: 17.83
+	Mm
		526710 TLE4_MOUSE (1-743): 1.35e-176: 526: 65.93		MSX1_MOUSE (119-283): 4.07e-35: 131: 34.12
+	Hs
		620142 TLE1_HUMAN (1-743): 2.32e-174: 520: 65.46		PAX7_HUMAN (31-325): 9.12e-36: 137: 18.15
+	Hs
		641377 TLE1_HUMAN (1-743): 2.32e-174: 520: 65.46		PAX6_HUMAN (31-325): 3.83e-36: 136: 17.83
+	Hs
		724224 TLE1_HUMAN (1-743): 2.32e-174: 520: 65.46		MSX2_HUMAN (96-296): 1.01e-34: 129: 30.88
+	Hs
		882123 TLE4_HUMAN (1-743): 3.3e-176: 525: 65.93		GSC_HUMAN (3-275): 1.57e-32: 123: 20.44
+	Hs
		882121 TLE1_HUMAN (1-743): 2.32e-174: 520: 65.46		GSC_HUMAN (3-275): 1.57e-32: 123: 20.44
+	Hs
		980956 TLE4_HUMAN (1-743): 3.3e-176: 525: 65.93		VSX1_HUMAN (8-295): 8.05e-30: 118: 23.71
+	Hs
		839732 TLE1_HUMAN (1-743): 2.32e-174: 520: 65.46		LHX2_HUMAN (119-316): 2.84e-30: 120: 19.70
+	Hs
		211838 TLE2_HUMAN (1-743): 0: 552: 100.00		TLX3_HUMAN (177-238): 2.09e-13: 71.2: 59.68
+	Hs
		980675 TLE2_HUMAN (1-743): 0: 552: 100.00		EMX2_HUMAN (176-236): 1.21e-12: 68.6: 55.74
+	Hs
		679098 TLE4_HUMAN (1-743): 3.3e-176: 525: 65.93		TLX1_HUMAN (170-254): 2.9e-15: 77: 50.59
+	Hs
		213323 TLE4_HUMAN (1-743): 3.3e-176: 525: 65.93		TLX2_HUMAN (170-238): 3.67e-14: 73.6: 56.52
+	Hs
		679096 TLE1_HUMAN (1-743): 2.32e-174: 520: 65.46		TLX1_HUMAN (170-254): 2.9e-15: 77: 50.59
+	Hs
		211840 TLE4_HUMAN (1-743): 3.3e-176: 525: 65.93		TLX3_HUMAN (177-238): 2.09e-13: 71.2: 59.68
+	Hs
		213321 TLE1_HUMAN (1-743): 2.32e-174: 520: 65.46		TLX2_HUMAN (170-238): 3.67e-14: 73.6: 56.52
+	Hs
		211837 TLE1_HUMAN (1-743): 2.32e-174: 520: 65.46		TLX3_HUMAN (177-238): 2.09e-13: 71.2: 59.68