HitPredict

Interactor 1: TLE3 (Q04726)
Transducin-like enhancer protein 3 (Enhancer of split groucho-like protein 3) (ESG3)
Gene: TLE3

Interactor 2: FOXC1 (Q12948)
Forkhead box protein C1 (Forkhead-related protein FKHL7) (Forkhead-related transcription factor 3) (FREAC-3)
Gene: FOXC1

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.479

Property	Details
Experiments	34551306
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005634 - nucleus GO:0005654 - nucleoplasm
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 772 Hs			1 553
+	Hs
		980855 TLE3_HUMAN (1-772): 0: 583: 100.00		FOXB1_HUMAN (68-371): 2.29e-49: 175: 32.08
+	Hs
		980741 TLE3_HUMAN (1-772): 0: 583: 100.00		FOXI1_HUMAN (40-316): 2.07e-45: 166: 35.02
+	Hs
		980742 TLE3_HUMAN (1-772): 0: 583: 100.00		FOXL1_HUMAN (42-371): 4.37e-45: 164: 30.42
+	Hs
		877704 TLE3_HUMAN (1-772): 0: 583: 100.00		FOXA1_HUMAN (14-357): 6.54e-35: 139: 30.52
+	Hs
		877992 TLE3_HUMAN (1-772): 0: 583: 100.00		FOXA3_HUMAN (7-279): 3.13e-35: 137: 34.80
+	Hs
		980641 TLE1_HUMAN (1-772): 0: 538: 77.42		FOXB1_HUMAN (68-371): 2.29e-49: 175: 32.08
+	Hs
		980669 TLE1_HUMAN (1-772): 0: 538: 77.42		FOXA2_HUMAN (50-369): 5.13e-48: 175: 30.79
+	Hs
		980951 TLE4_HUMAN (1-772): 9.37e-179: 533: 80.65		FOXB1_HUMAN (68-371): 2.29e-49: 175: 32.08
+	Hs
		980595 TLE1_HUMAN (1-772): 0: 538: 77.42		FOXI1_HUMAN (40-316): 2.07e-45: 166: 35.02
+	Hs
		980596 TLE1_HUMAN (1-772): 0: 538: 77.42		FOXL1_HUMAN (42-371): 4.37e-45: 164: 30.42
+	Hs
		980930 TLE4_HUMAN (1-772): 9.37e-179: 533: 80.65		FOXI1_HUMAN (40-316): 2.07e-45: 166: 35.02
+	Hs
		980931 TLE4_HUMAN (1-772): 9.37e-179: 533: 80.65		FOXL1_HUMAN (42-371): 4.37e-45: 164: 30.42
+	Hs
		877602 TLE1_HUMAN (1-772): 0: 538: 77.42		FOXG1_HUMAN (35-367): 2.29e-37: 146: 25.57
+	Hs
		877703 TLE1_HUMAN (1-772): 0: 538: 77.42		FOXA1_HUMAN (14-357): 6.54e-35: 139: 30.52
+	Hs
		877990 TLE1_HUMAN (1-772): 0: 538: 77.42		FOXA3_HUMAN (7-279): 3.13e-35: 137: 34.80
+	Rn
		88552 D3ZCM7_RAT (1-772): 3.17e-177: 528: 77.94		FOXG1_RAT (26-367): 7.74e-35: 139: 25.21
+	Mm
		1141982 TLE1_MOUSE (1-772): 1.82e-174: 522: 78.22		FOXG1_MOUSE (26-367): 6.85e-35: 139: 25.21
+	Dm
		558360 GROU_DROME (1-772): 4.17e-136: 421: 57.20		SLP1_DROME (75-202): 8.54e-47: 168: 45.31
+	Hs
		877991 TLE2_HUMAN (1-772): 4.46e-145: 445: 62.10		FOXA3_HUMAN (7-279): 3.13e-35: 137: 34.80
+	Dm
		558388 GROU_DROME (1-772): 4.17e-136: 421: 57.20		Q961V5_DROME (58-263): 4.82e-35: 136: 28.91