HitPredict

Interactor 1: TLE3 (Q04726)
Transducin-like enhancer protein 3 (Enhancer of split groucho-like protein 3) (ESG3)
Gene: TLE3

Interactor 2: NFIX (Q14938)
Nuclear factor 1 X-type (NF1-X) (Nuclear factor 1/X) (CCAAT-box-binding transcription factor) (CTF) (Nuclear factor I/X) (NF-I/X) (NFI-X) (TGGCA-binding protein)
Gene: NFIX

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.56	0.60	0.584

Property	Details
Experiments	35140242, 37689310
Identification Methods	proximity labelling technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005634 - nucleus
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 772 Hs			1 502
+	Hs
		980606 TLE1_HUMAN (1-772): 0: 538: 77.42		NFIX_HUMAN (1-502): 6.2e-159: 462: 100.00
+	Hs
		980739 TLE3_HUMAN (1-772): 0: 583: 100.00		NFIA_HUMAN (1-502): 1.62e-118: 359: 66.47
+	Hs
		443171 TLE3_HUMAN (1-772): 0: 583: 100.00		NFIC_HUMAN (3-502): 5.37e-114: 348: 53.43
+	Hs
		980594 TLE1_HUMAN (1-772): 0: 538: 77.42		NFIA_HUMAN (1-502): 1.62e-118: 359: 66.47
+	Hs
		135107 TLE3_HUMAN (1-772): 0: 583: 100.00		NFIB_HUMAN (1-419): 4.58e-101: 311: 58.69
+	Hs
		443170 TLE1_HUMAN (1-772): 0: 538: 77.42		NFIC_HUMAN (3-502): 5.37e-114: 348: 53.43
+	Hs
		135106 TLE1_HUMAN (1-772): 0: 538: 77.42		NFIB_HUMAN (1-419): 4.58e-101: 311: 58.69
+	Hs
		993425 TLE5_HUMAN (1-200): 1.22e-100: 310: 62.19		NFIX_HUMAN (1-502): 6.2e-159: 462: 100.00
+	Hs
		993404 TLE5_HUMAN (1-200): 1.22e-100: 310: 62.19		NFIA_HUMAN (1-502): 1.62e-118: 359: 66.47
+	Hs
		135111 TLE5_HUMAN (1-200): 1.22e-100: 310: 62.19		NFIB_HUMAN (1-419): 4.58e-101: 311: 58.69
+	Hs
		443244 TBL1R_HUMAN (571-771): 3.06e-46: 174: 15.07		NFIC_HUMAN (3-502): 5.37e-114: 348: 53.43
+	Hs
		135156 TBL1R_HUMAN (571-771): 3.06e-46: 174: 15.07		NFIB_HUMAN (1-419): 4.58e-101: 311: 58.69
+	Hs
		443230 SNR40_HUMAN (509-677): 5.35e-09: 60.8: 26.52		NFIC_HUMAN (3-502): 5.37e-114: 348: 53.43
+	Hs
		123919 TLE5_HUMAN (1-200): 1.22e-100: 310: 62.19		SPT5H_HUMAN (144-357): 1.74e-12: 71.9: 13.60
+	Hs
		1137768 POC1B_HUMAN (290-512): 1.47e-23: 106: 9.78		OBSCN_HUMAN (66-465): 5.33e-45: 172: 15.35
+	Hs
		124015 POC1A_HUMAN (325-603): 2.33e-51: 186: 14.59		SPT5H_HUMAN (144-357): 1.74e-12: 71.9: 13.60
+	Hs
		302275 WDR5_HUMAN (284-560): 2.42e-32: 130: 9.12		SC31A_HUMAN (196-498): 3.9e-11: 67.7: 9.78
+	Mm
		903669 WDR5_MOUSE (284-560): 2.42e-32: 130: 9.12		KMT2C_MOUSE (164-497): 1.15e-09: 63.5: 10.79
+	Hs
		903374 WDR5_HUMAN (284-560): 2.42e-32: 130: 9.12		KMT2C_HUMAN (197-498): 9.61e-09: 60.4: 9.61
+	Hs
		124040 SNR40_HUMAN (509-677): 5.35e-09: 60.8: 26.52		SPT5H_HUMAN (144-357): 1.74e-12: 71.9: 13.60