HitPredict

Interactor 1: TLE4 (Q04727)
Transducin-like enhancer protein 4 (Grg-4) (Groucho-related protein 4)
Gene: TLE4

Interactor 2: PAX8 (Q06710)
Paired box protein Pax-8
Gene: PAX8

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.479

Property	Details
Experiments	35140242
Identification Methods	proximity labelling technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005634 - nucleus GO:0005654 - nucleoplasm
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 773 Hs			1 450
+	Hs
		641379 TLE4_HUMAN (1-773): 0: 622: 100.00		PAX6_HUMAN (6-413): 3.44e-95: 294: 30.26
+	Hs
		620144 TLE4_HUMAN (1-773): 0: 622: 100.00		PAX7_HUMAN (9-450): 1.04e-90: 286: 27.94
+	Mm
		623700 TLE4_MOUSE (1-773): 0: 623: 99.61		PAX3_MOUSE (9-446): 8.38e-90: 283: 31.50
+	Hs
		980588 TLE1_HUMAN (8-773): 0: 580: 86.27		PAX8_HUMAN (1-450): 2.59e-103: 316: 100.00
+	Hs
		641377 TLE1_HUMAN (8-773): 0: 580: 86.27		PAX6_HUMAN (6-413): 3.44e-95: 294: 30.26
+	Hs
		620142 TLE1_HUMAN (8-773): 0: 580: 86.27		PAX7_HUMAN (9-450): 1.04e-90: 286: 27.94
+	Hs
		971652 TLE4_HUMAN (1-773): 0: 622: 100.00		PAX5_HUMAN (5-448): 1.42e-74: 240: 43.02
+	Hs
		980733 TLE3_HUMAN (8-773): 0: 539: 80.90		PAX8_HUMAN (1-450): 2.59e-103: 316: 100.00
+	Hs
		973842 TLE1_HUMAN (8-773): 0: 580: 86.27		PAX2_HUMAN (2-448): 4.91e-82: 260: 47.88
+	Hs
		641378 TLE3_HUMAN (8-773): 0: 539: 80.90		PAX6_HUMAN (6-413): 3.44e-95: 294: 30.26
+	Hs
		620143 TLE3_HUMAN (8-773): 0: 539: 80.90		PAX7_HUMAN (9-450): 1.04e-90: 286: 27.94
+	Hs
		878398 TLE4_HUMAN (1-773): 0: 622: 100.00		PAX9_HUMAN (6-346): 1.35e-58: 197: 33.62
+	Hs
		973843 TLE3_HUMAN (8-773): 0: 539: 80.90		PAX2_HUMAN (2-448): 4.91e-82: 260: 47.88
+	Hs
		878395 TLE1_HUMAN (8-773): 0: 580: 86.27		PAX9_HUMAN (6-346): 1.35e-58: 197: 33.62
+	Hs
		878397 TLE3_HUMAN (8-773): 0: 539: 80.90		PAX9_HUMAN (6-346): 1.35e-58: 197: 33.62
+	Hs
		980956 TLE4_HUMAN (1-773): 0: 622: 100.00		VSX1_HUMAN (142-252): 9.67e-10: 61.9: 18.92
+	Hs
		878396 TLE2_HUMAN (8-773): 3.63e-157: 476: 65.19		PAX9_HUMAN (6-346): 1.35e-58: 197: 33.62
+	Hs
		980659 TLE1_HUMAN (8-773): 0: 580: 86.27		VSX1_HUMAN (142-252): 9.67e-10: 61.9: 18.92
+	Hs
		980893 TLE3_HUMAN (8-773): 0: 539: 80.90		VSX1_HUMAN (142-252): 9.67e-10: 61.9: 18.92
+	Dm
		185801 GROU_DROME (8-773): 1.23e-144: 443: 59.14		PAX6_DROME (124-446): 1.57e-22: 102: 13.68