Interactor 1: KPCT (Q04759)
Protein kinase C theta type (EC 2.7.11.13) (nPKC-theta)
Gene: PRKCQ

Interactor 2: CAR11 (Q9BXL7)
Caspase recruitment domain-containing protein 11 (CARD-containing MAGUK protein 1) (Carma 1)
Gene: CARD11

Species: Homo sapiens

Source: intact

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.84 0.60 0.711

The method score is based on:

Property Details
Experiments 21157432, 22528498, 19706536, 20164171, 16356855
Identification Methods affinity chromatography technology, enzymatic study, anti tag coimmunoprecipitation
Interaction Type physical association, direct interaction

The annotation score is based on:

Property Details
Interacting Pfam domains -
Common GO terms GO:0001772 - immunological synapse
GO:0005829 - cytosol
GO:0005886 - plasma membrane
GO:0032743 - positive regulation of interleukin-2 production
GO:0035739 - CD4-positive, alpha-beta T cell proliferation
and 2 others

more...

Homologous interactions 12

Homologous interactions

Color coding for hit scores

1 706
Hs

1 1154
+ Mm
+ Hs
+ Hs
+ Hs
+ Mm
+ Rn
+ Rn
+ Hs
+ Dm
+ Dm
+ Mm
+ Mm

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Last updated: 15 Jul 2024