HitPredict

Interactor 1: RAN (P62826)
GTP-binding nuclear protein Ran (EC 3.6.5.-) (Androgen receptor-associated protein 24) (GTPase Ran) (Ras-like protein TC4) (Ras-related nuclear protein)
Gene: RAN

Interactor 2: ESR2 (Q92731)
Estrogen receptor beta (ER-beta) (Nuclear receptor subfamily 3 group A member 2)
Gene: ESR2

Species: Homo sapiens

Source: intact

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.62	0.60	0.611

Property	Details
Experiments	29509190, 21951318
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0000785 - chromatin GO:0005634 - nucleus GO:0005654 - nucleoplasm
Homologous interactions	18

Homologous interactions

Color coding for hit scores

	1 216 Hs			1 530
+	Hs
		1145047 RAB35_HUMAN (1-188): 1.33e-82: 245: 29.47		ESR2_HUMAN (1-530): 2.39e-157: 460: 100.00
+	Hs
		981335 RAB1A_HUMAN (1-196): 2.37e-81: 242: 28.00		ESR2_HUMAN (1-530): 2.39e-157: 460: 100.00
+	Hs
		1367234 RAB1B_HUMAN (4-195): 2.99e-80: 239: 28.72		ESR2_HUMAN (1-530): 2.39e-157: 460: 100.00
+	Hs
		396914 RAB1B_HUMAN (4-195): 2.99e-80: 239: 28.72		ESR1_HUMAN (9-529): 3.59e-138: 413: 44.56
+	Hs
		395842 RAN_HUMAN (1-216): 1.48e-79: 238: 100.00		ESR1_HUMAN (9-529): 3.59e-138: 413: 44.56
+	Hs
		395835 RB11A_HUMAN (4-208): 4.29e-78: 235: 26.67		ESR1_HUMAN (9-529): 3.59e-138: 413: 44.56
+	Hs
		404405 RAB1B_HUMAN (4-195): 2.99e-80: 239: 28.72		GCR_HUMAN (3-495): 1.13e-103: 330: 22.64
+	Hs
		956767 RAB10_HUMAN (11-177): 3.92e-29: 109: 33.14		ESR2_HUMAN (1-530): 2.39e-157: 460: 100.00
+	Hs
		403957 RAN_HUMAN (1-216): 1.48e-79: 238: 100.00		GCR_HUMAN (3-495): 1.13e-103: 330: 22.64
+	Hs
		403943 RAB8A_HUMAN (1-203): 9.08e-79: 236: 24.76		GCR_HUMAN (3-495): 1.13e-103: 330: 22.64
+	Hs
		403953 RB11A_HUMAN (4-208): 4.29e-78: 235: 26.67		GCR_HUMAN (3-495): 1.13e-103: 330: 22.64
+	Hs
		848099 RAN_HUMAN (1-216): 1.48e-79: 238: 100.00		NR4A2_HUMAN (23-501): 3.26e-98: 311: 23.30
+	Hs
		395794 RAB10_HUMAN (11-177): 3.92e-29: 109: 33.14		ESR1_HUMAN (9-529): 3.59e-138: 413: 44.56
+	Hs
		403945 RAB10_HUMAN (11-177): 3.92e-29: 109: 33.14		GCR_HUMAN (3-495): 1.13e-103: 330: 22.64
+	Hs
		403814 RAB4A_HUMAN (11-169): 1.54e-27: 105: 34.57		GCR_HUMAN (3-495): 1.13e-103: 330: 22.64
+	Hs
		442911 RAN_HUMAN (1-216): 1.48e-79: 238: 100.00		PRGR_HUMAN (149-459): 2.27e-41: 161: 32.82
+	Hs
		519916 RAN_HUMAN (1-216): 1.48e-79: 238: 100.00		ANDR_HUMAN (149-407): 8.13e-38: 150: 32.59
+	Hs
		519893 RAB10_HUMAN (11-177): 3.92e-29: 109: 33.14		ANDR_HUMAN (149-407): 8.13e-38: 150: 32.59