HitPredict

Interactor 1: PTN12 (Q05209)
Tyrosine-protein phosphatase non-receptor type 12 (EC 3.1.3.48) (PTP-PEST) (Protein-tyrosine phosphatase G1) (PTPG1)
Gene: PTPN12

Interactor 2: CASL (Q14511)
Enhancer of filamentation 1 (hEF1) (CRK-associated substrate-related protein) (CAS-L) (CasL) (Cas scaffolding protein family member 2) (CASS2) (Neural precursor cell expressed developmentally down-regulated protein 9) (NEDD-9) (Renal carcinoma antigen NY-REN-12) (p105) [Cleaved into: Enhancer of filamentation 1 p55]
Gene: NEDD9

Species: Homo sapiens

Source: biogrid

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.41	0.60	0.501

Property	Details
Experiments	9748319
Identification Methods	pull down
Interaction Type	direct interaction

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005634 - nucleus GO:0005654 - nucleoplasm GO:0005737 - cytoplasm GO:0005829 - cytosol GO:0005925 - focal adhesion
Homologous interactions	8

Homologous interactions

Color coding for hit scores

	1 780 Hs			1 834
+	Hs
		985955 PTN11_HUMAN (7-351): 1.65e-124: 387: 31.48		CASL_HUMAN (1-834): 0: 614: 100.00
+	Hs
		882255 PTN12_HUMAN (1-780): 0: 586: 100.00		BCAR1_HUMAN (1-832): 3e-84: 289: 33.44
+	Hs
		983518 PTN12_HUMAN (1-780): 0: 586: 100.00		CASS4_HUMAN (4-829): 2.76e-79: 273: 22.64
+	Mm
		728829 PTN12_MOUSE (1-780): 0: 560: 83.10		BCAR1_MOUSE (1-832): 1.75e-82: 284: 32.86
+	Hs
		199511 PTN12_HUMAN (1-780): 0: 586: 100.00		EFS_HUMAN (7-264): 5.8e-20: 96.7: 26.34
+	Hs
		573636 PTN1_HUMAN (27-409): 1.5e-127: 389: 24.46		BCAR1_HUMAN (1-832): 3e-84: 289: 33.44
+	Hs
		882258 PTN11_HUMAN (7-351): 1.65e-124: 387: 31.48		BCAR1_HUMAN (1-832): 3e-84: 289: 33.44
+	Rn
		783508 PTN11_RAT (7-351): 1.11e-123: 385: 31.48		BCAR1_RAT (4-832): 1.74e-83: 289: 33.30